Chemoradiotherapy of locally-advanced non-small cell lung cancer: Analysis of radiation dose-response, chemotherapy and survival-limiting toxicity effects indicates a low α/β ratio.
Chemotherapy
Dose-escalation
NSCLC
Radiotherapy
Toxicity
Journal
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
ISSN: 1879-0887
Titre abrégé: Radiother Oncol
Pays: Ireland
ID NLM: 8407192
Informations de publication
Date de publication:
02 2020
02 2020
Historique:
received:
23
01
2019
revised:
21
06
2019
accepted:
22
07
2019
pubmed:
24
8
2019
medline:
15
4
2021
entrez:
24
8
2019
Statut:
ppublish
Résumé
To analyse changes in 2-year overall survival (OS OS A model including chemotherapy effects and survival-limiting toxicity described the data significantly better than simpler models (p < 10 Fitted dose-response curves indicate that gains of ~10% in OS
Identifiants
pubmed: 31439448
pii: S0167-8140(19)33019-1
doi: 10.1016/j.radonc.2019.07.026
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
58-65Subventions
Organisme : Medical Research Council
ID : MC_PC_12001/2
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_UU_00001/2
Pays : United Kingdom
Informations de copyright
Copyright © 2019 Elsevier B.V. All rights reserved.