[Research advance in circular RNAs].

Animals RNA / genetics RNA, Circular Research / trends

Journal

Sheng li xue bao : [Acta physiologica Sinica]
ISSN: 0371-0874
Titre abrégé: Sheng Li Xue Bao
Pays: China
ID NLM: 20730130R

Informations de publication

Date de publication:
25 Aug 2019
Historique:
entrez: 24 8 2019
pubmed: 24 8 2019
medline: 27 9 2019
Statut: ppublish

Résumé

Circular RNAs (circRNAs) are a class of endogenous, covalently closed, single-stranded RNA without 3'-poly(A) and 5'-cap structures. CircRNAs are characterized by universality, diversity, stability and conservation, and have been found to regulate mammalian transcription and be translated into proteins. In this review, we summarized the biogenesis, classification, expression, distribution, biological functions and regulation of circRNAs. In addition, we discussed the association of circRNAs with diseases and the methods for identification and characterization of circRNAs. Finally, we speculated the application prospect and research direction of circRNAs.

Identifiants

PMID: 31440759
pubmed: 31440759

Substances chimiques

RNA, Circular 0
RNA 63231-63-0

Types de publication

Journal Article Review

Langues

chi

Sous-ensembles de citation

IM

Pagination

613-624

Auteurs

Yu-Han Qi (YH)

School of Stomatology, Tongji University, Shanghai 200092, China.

Ze-Peng Liu (ZP)

School of Stomatology, Tongji University, Shanghai 200092, China.

Wei-Jie Zhang (WJ)

School of Stomatology, Tongji University, Shanghai 200092, China.

Ping-Fan Shi (PF)

Department of Regenerative Medicine, School of Medicine, Tongji University, Shanghai 200092, China.

Shuang Qin (S)

Department of Regenerative Medicine, School of Medicine, Tongji University, Shanghai 200092, China.

Zhi-Hua Shao (ZH)

Department of Regenerative Medicine, School of Medicine, Tongji University, Shanghai 200092, China. zhihua_shao@163.com.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › [Research advance in circular RNAs].
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › [Research advance in circular RNAs].
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › ARN circulaire › [Research advance in circular RNAs].
questionsmedicales.fr › Disciplines des sciences naturelles › Science › Recherche › [Research advance in circular RNAs].