Gatifloxacin-1,2,3-triazole-isatin hybrids and their antimycobacterial activities.


Journal

Archiv der Pharmazie
ISSN: 1521-4184
Titre abrégé: Arch Pharm (Weinheim)
Pays: Germany
ID NLM: 0330167

Informations de publication

Date de publication:
Oct 2019
Historique:
received: 07 05 2019
revised: 18 07 2019
accepted: 23 07 2019
pubmed: 24 8 2019
medline: 19 2 2020
entrez: 24 8 2019
Statut: ppublish

Résumé

A series of gatifloxacin-1,2,3-triazole-isatin hybrids 8a-l were designed, synthesized, and screened for their in vitro antimycobacterial activity as well as cytotoxicity toward Chinese Hamster Ovary (CHO) cells. The synthesized hybrids showed considerable activity against MTB H

Identifiants

pubmed: 31441087
doi: 10.1002/ardp.201900135
doi:

Substances chimiques

Antitubercular Agents 0
Triazoles 0
Isatin 82X95S7M06
Gatifloxacin L4618BD7KJ

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e1900135

Informations de copyright

© 2019 Deutsche Pharmazeutische Gesellschaft.

Auteurs

Zhen Ding (Z)

Department of Pharmacy, Bozhou People's Hospital, Bozhou, China.

Panfei Hou (P)

Department of Clinical Laboratory, Lianshui County People's Hospital, Lianshui, China.

Bi Liu (B)

School of Nuclear Technology and Chemistry and Biology, Hubei University of Science and Technology, Xianning, China.

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Classifications MeSH