An unusual cause of paraesthesia in a neo-adjuvant gastro-oesophageal cancer.


Journal

BMJ case reports
ISSN: 1757-790X
Titre abrégé: BMJ Case Rep
Pays: England
ID NLM: 101526291

Informations de publication

Date de publication:
22 Aug 2019
Historique:
entrez: 25 8 2019
pubmed: 25 8 2019
medline: 7 2 2020
Statut: epublish

Résumé

There is ongoing debate about the best neo-adjuvant strategy for localised resectable oesophageal cancer, however chemotherapy is often employed. Both oesophageal cancer and cisplatin carry an increased risk of thrombosis. Here, we look at an unusual finding in a previously fit woman who presented following neo-adjuvant chemotherapy for resectable oesophageal cancer with increasing difficulty in walking and lower limb paraesthesia. This case looks particularly at the diagnostic challenge and concerns raised in a patient undergoing radical treatment as well as the challenge of complications secondary to treatment with chemotherapy. Willingness to reassess and revisit is a vital part of the diagnostic process. Vascular complications of a disease can be notorious to diagnose and, as in this case can mimic arguably more logical diagnoses. Cancer care provides the unique challenge of investigating unusual presentations related both to disease and treatment.

Identifiants

pubmed: 31444258
pii: 12/8/e225450
doi: 10.1136/bcr-2018-225450
pmc: PMC6721004
pii:
doi:

Substances chimiques

Antineoplastic Agents 0
Cisplatin Q20Q21Q62J

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

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Auteurs

Sarah Derby (S)

Clinical Oncology, Beatson West of Scotland Cancer Centre, Glasgow, UK.

Janet Graham (J)

Medical Oncology, Beatson West of Scotland Cancer Centre, Glasgow, UK.

David McIntosh (D)

Medical Oncology, Beatson West of Scotland Cancer Centre, Glasgow, UK.

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Classifications MeSH