A New Lead Identification Strategy: Screening an sp


Journal

ChemMedChem
ISSN: 1860-7187
Titre abrégé: ChemMedChem
Pays: Germany
ID NLM: 101259013

Informations de publication

Date de publication:
06 11 2019
Historique:
received: 03 07 2019
revised: 18 08 2019
pubmed: 25 8 2019
medline: 29 9 2020
entrez: 25 8 2019
Statut: ppublish

Résumé

Although the advantages of sp

Identifiants

pubmed: 31444850
doi: 10.1002/cmdc.201900398
doi:

Substances chimiques

Aza Compounds 0
Norbornanes 0
Receptors, Ghrelin 0
Small Molecule Libraries 0
Water 059QF0KO0R

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1840-1848

Subventions

Organisme : JPSP KAKENHI
ID : 16K18912
Pays : International
Organisme : Kitasato University Research Grant for Young Researchers
ID : (none)
Pays : International

Informations de copyright

© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Références

F. Lovering, J. Bikker, C. Humblet, J. Med. Chem. 2009, 52, 6752-6756.
F. Lovering, MedChemComm 2013, 4, 515-519.
S. Sun, Q. Jia, A. Y. Zenova, M. S. Wilson, S. Chowdhury, T. Focken, J. Li, S. Decker, M. E. Grimwood, J.-C. Andrez, I. Hemeon, T. Sheng, C.-A. Chen, A. White, D. H. Hackos, L. Deng, G. Bankar, K. Khakh, E. Chang, R. Kwan, S. Lin, K. Nelkenbrecher, B. D. Sellers, A. G. DiPasquale, J. Chang, J. Pang, L. Sojo, A. Lindgren, M. Waldbrook, D. P. Sutherlin, D. F. Ortwine, C. M. Dehnhardt, J. Med. Chem. 2019, 62, 908-927.
T. Knoepfel, P. Furet, R. Mah, N. Buschmann, C. Leblanc, S. Ripoche, D. Graus-Porta, M. Wartmann, I. Galuba, R. A. Fairhurst, ACS Med. Chem. Lett. 2018, 9, 215-220.
J. Reuberson, H. Horsley, R. J. Franklin, D. Ford, J. Neuss, D. Brookings, Q. Huang, B. Vanderhoydonck, L.-J. Gao, M.-Y. Jang, P. Herdewijn, A. Ghawalkar, F. Fallah-Arani, A. R. Kahn, J. Henshall, M. Jairaj, S. Malcolm, E. Ward, L. Shuttleworth, Y. Lin, S. Li, T. Louat, M. Waer, J. Herman, A. Payne, T. Ceska, C. Doyle, W. Pitt, M. Calmiano, M. Augustin, S. Steinbacher, A. Lammens, R. Allen, J. Med. Chem. 2018, 61, 6705-6723.
K. Hirata, M. Kotoku, N. Seki, T. Maeda, K. Maeda, S. Hirashima, T. Sakai, S. Obika, A. Hori, Y. Hase, T. Yamaguchi, Y. Katsuda, M. Kamada, T. Adachi, M. Noguchi, S. Doi, P. Crowe, E. Bradley, R. Steensma, H. Tao, M. Fenn, R. Babine, X. Li, S. Thacher, H. Hashimoto, M. Shiozaki, ACS Med. Chem. Lett. 2016, 7, 23-27.
S. Dandapani, L. A. Marcaurelle, Nat. Chem. Biol. 2010, 6, 861-863.
D. G. Brown, J. Boström, J. Med. Chem. 2016, 59, 4443-4458.
C. F. Stratton, D. J. Newman, D. S. Tan, Bioorg. Med. Chem. Lett. 2015, 25, 4802-4807.
P. A. Clemons, N. E. Bodycombe, H. A. Carrinski, J. A. Wilson, A. F. Shamji, B. K. Wagner, A. N. Koehler, S. L. Schreiber, Proc. Natl. Acad. Sci. USA 2010, 107, 18787-18792.
S. Z. Tasker, A. E. Cowfer, P. J. Hergenrother, Org. Lett. 2018, 20, 5894-5898.
N. G. Paciaroni, R. Ratnayake, J. H. Matthews, V. M. Norwood, A. C. Arnold, L. H. Dang, H. Luesch, R. W. Huigens, Chem. Eur. J. 2017, 23, 4327-4335.
N. V. S. Birudukota, R. Franke, B. Hofer, Org. Biomol. Chem. 2016, 14, 3821-3837.
S. Stotani, C. Lorenz, M. Winkler, F. Medda, E. Picazo, R. O. Martinez, A. Karawajczyk, J. Sanchez-Quesada, F. Giordanetto, ACS Comb. Sci. 2016, 18, 330-336.
F. Issa, M. Kassiou, L. M. Rendina, Chem. Rev. 2011, 111, 5701-5722.
L. Wanka, K. Iqbal, P. R. Schreiner, Chem. Rev. 2013, 113, 3516-3604.
The CLogP value was calculated using ChemDraw Professional version 16.0.
A. Nadin, C. Hattotuwagama, I. Churcher, Angew. Chem. Int. Ed. 2012, 51, 1114-1122;
Angew. Chem. 2012, 124, 1140-1149.
F. Karaki, Y. Kabasawa, T. Yanagimoto, N. Umeda, Firman, Y. Urano, T. Nagano, Y. Otani, T. Ohwada, Chem. Eur. J. 2012, 18, 1127-1141.
Y. Otani, S. Futaki, T. Kiwada, Y. Sugiura, A. Muranaka, N. Kobayashi, M. Uchiyama, K. Yamaguchi, T. Ohwada, Tetrahedron 2006, 62, 11635-11644.
H. Fujii, T. Yamada, K. Hayashida, M. Kuwada, A. Hamasaki, K. Nobuhara, S. Ozeki, H. Nagase, Heterocycles 2012, 85, 2685-2691.
H. Fujii, N. Shimada, M. Ohtawa, F. Karaki, M. Koshizuka, K. Hayashida, M. Kamimura, K. Makino, T. Nagamitsu, H. Nagase, Tetrahedron 2017, 73, 5425-5429.
C. A. Lipinski, F. Lombardo, B. W. Dominy, P. J. Feeney, Adv. Drug Delivery Rev. 1997, 23, 3-25.
K. A. Chu, S. H. Yalkowsky, Int. J. Pharm. 2009, 373, 24-40.
M. Ishikawa, Y. Hashimoto, J. Med. Chem. 2011, 54, 1539-1554.
F. Mao, Q. Kong, W. Ni, X. Xu, D. Ling, Z. Lu, J. Li, ChemistryOpen 2016, 5, 357-368.
M. Hiramatsu, Y. Ichikawa, S. Tomoshige, M. Makishima, A. Muranaka, M. Uchiyama, T. Yamaguchi, Y. Hashimoto, M. Ishikawa, Chem. Asian J. 2016, 11, 2210-2217.
K. Miyano, Y. Sudo, A. Yokoyama, K. Hisaoka-Nakashima, N. Morioka, M. Takebayashi, Y. Nakata, Y. Higami, Y. Uezono, J. Pharmacol. Sci. 2014, 126, 302-309.
S. Mandadi, B. D. Roufogalis, Curr. Neuropharmacol. 2008, 6, 21-38.
J. D. Levine, N. Alessandri-Haber, Biochim. Biophys. Acta Mol. Basis Dis. 2007, 1772, 989-1003.
R. Brito, S. Sheth, D. Mukherjea, L. P. Rybak, V. Ramkumar, Cell 2014, 3, 517-545.
S. Mihara, T. Shibamoto, Allergy Asthma Clin. Immunol. 2015, 11, 11.
H.-J. Behrendt, T. Germann, C. Gillen, H. Hatt, R. Jostock, Br. J. Pharmacol. 2004, 141, 737-745.
H. Fujii, T. Takahashi, H. Nagase, Expert Opin. Ther. Pat. 2013, 23, 1181-1208.
H. Nagase, H. Fujii, Top. Curr. Chem. 2011, 299, 29-62.
T. Che, S. Majumdar, S. A. Zaidi, P. Ondachi, J. D. McCorvy, S. Wang, P. D. Mosier, R. Uprety, E. Vardy, B. E. Krumm, G. W. Han, M.-Y. Lee, E. Pardon, J. Steyaert, X.-P. Huang, R. T. Strachan, A. R. Tribo, G. W. Pasternak, F. I. Carroll, R. C. Stevens, V. Cherezov, V. Katritch, D. Wacker, B. L. Roth, Cell 2018, 172, 55-67.
S. A. Graf, J. M. Garcia, Drug Des. Dev. Ther. 2017, 11, 2325-2331.
A. Moulin, L. Demange, J. Ryan, D. Mousseaux, P. Sanchez, G. Bergé, D. Gagne, D. Perrissoud, V. Locatelli, A. Torsello, J.-C. Galleyrand, J.-A. Fehrentz, J. Martinez, J. Med. Chem. 2008, 51, 689-693.
Y. Yin, Y. Li, W. Zhang, Int. J. Mol. Sci. 2014, 15, 4837-4855.
M. Hansson, J. Pemberton, O. Engkvist, I. Feierberg, L. Brive, P. Jarvis, L. Zander-Balderud, H. Chen, J. Biomol. Screening 2014, 19, 727-737.
C. Chavkin, I. F. James, A. Goldstein, Science 1982, 215, 413-415.
V. T. Ramirez, W. E. P. A. van Oeffelen, C. Torres-Fuentes, B. Chru′scicka, C. Druelle, A. V. Golubeva, M. van de Wouw, T. G. Dinan, J. F. Cryan, H. Schellekens, FASEB J. 2019, 33, 518-531.
S. S. Schattauer, J. R. Kuhar, A. Song, C. Chavkin, Cell Signal. 2017, 32, 59-65.
T. R. Chan, R. Hilgraf, K. B. Sharpless, V. V. Fokin, Org. Lett. 2004, 6, 2853-2855.
J. Kollonitsch, O. Fuchs, V. Gábor, Nature 1955, 175, 346-346.
Y. Meguro, K. Miyano, S. Hirayama, Y. Yoshida, N. Ishibashi, T. Ogino, Y. Fujii, S. Manabe, M. Eto, M. Nonaka, H. Fujii, Y. Ueta, M. Narita, N. Sata, T. Yada, Y. Uezono, J. Pharmacol. Sci. 2018, 137, 67-75.
K. Miyano, K. Minami, T. Yokoyama, K. Ohbuchi, T. Yamaguchi, S. Murakami, S. Shiraishi, M. Yamamoto, M. Matoba, Y. Uezono, Anesth. Analg. 2015, 120, 790-798.
N. Fujitsuka, A. Asakawa, A. Morinaga, M. S. Amitani, H. Amitani, G. Katsuura, Y. Sawada, Y. Sudo, Y. Uezono, E. Mochiki, I. Sakata, T. Sakai, K. Hanazaki, T. Yada, K. Yakabi, E. Sakuma, T. Ueki, A. Niijima, K. Nakagawa, N. Okubo, H. Takeda, M. Asaka, A. Inui, Mol. Psychiatry 2016, 21, 1613-1623.
B. Callaghan, S. Kosari, R. V. Pustovit, D. M. Sartor, D. Ferens, K. Ban, J. Baell, T. V. Nguyen, L. R. Rivera, J. A. Brock, J. B. Furness, Br. J. Pharmacol. 2014, 171, 1275-1286.

Auteurs

Fumika Karaki (F)

Laboratory of Medicinal Chemistry, School of Pharmacy, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
Medicinal Research Laboratories, School of Pharmacy, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo, 108-8641, Japan.

Sho Umemoto (S)

Laboratory of Medicinal Chemistry, School of Pharmacy, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo, 108-8641, Japan.

Karin Ashizawa (K)

Laboratory of Medicinal Chemistry, School of Pharmacy, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
Division of Cancer Pathophysiology, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

Tomoya Oki (T)

Laboratory of Medicinal Chemistry, School of Pharmacy, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo, 108-8641, Japan.

Noriko Sato (N)

Analytical Unit for Organic Chemistry, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo, 108-8641, Japan.

Takumi Ogino (T)

Laboratory of Medicinal Chemistry, School of Pharmacy, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
Division of Cancer Pathophysiology, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

Naoto Ishibashi (N)

Laboratory of Medicinal Chemistry, School of Pharmacy, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
Division of Cancer Pathophysiology, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

Ryoto Someya (R)

Laboratory of Medicinal Chemistry, School of Pharmacy, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
Division of Cancer Pathophysiology, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

Kanako Miyano (K)

Division of Cancer Pathophysiology, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

Shigeto Hirayama (S)

Laboratory of Medicinal Chemistry, School of Pharmacy, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
Medicinal Research Laboratories, School of Pharmacy, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo, 108-8641, Japan.

Yasuhito Uezono (Y)

Division of Cancer Pathophysiology, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
Division of Supportive Care Research, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
Innovation Center for Supportive, Palliative and Psychosocial Care, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
Department of Comprehensive Oncology, Graduate School of Biomedical Sciences, Nagasaki University, 1-12-4 Sakamoto, Nagasaki, 852-8523, Japan.

Hideaki Fujii (H)

Laboratory of Medicinal Chemistry, School of Pharmacy, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
Medicinal Research Laboratories, School of Pharmacy, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo, 108-8641, Japan.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH