Clinical predictors of malignancy in palatal salivary gland tumors.
clinical decision-making
diagnosis
minor salivary glands
oral cancer
palate
salivary gland neoplasms
Journal
Oral diseases
ISSN: 1601-0825
Titre abrégé: Oral Dis
Pays: Denmark
ID NLM: 9508565
Informations de publication
Date de publication:
Nov 2019
Nov 2019
Historique:
received:
27
04
2019
revised:
12
08
2019
accepted:
17
08
2019
pubmed:
25
8
2019
medline:
1
1
2020
entrez:
25
8
2019
Statut:
ppublish
Résumé
To establish a predictive clinical index of malignancy risk in palatal salivary gland tumors (PSGT). One hundred cases of PSGT were evaluated. Clinical data were retrieved from the patient's files. Representative clinical photographs of each tumor were evaluated to identify clinical features suggestive of a malignant tumor. Features significantly associated with malignancy were included in a binary logistic regression model. Malignant tumors were more common in the hard palate, in women and in older patients. Features associated with a malignant diagnosis included pain (p = .017), irregular surface (p = .004), bluish/purple coloration (p < .001), ulceration (p = .005), and telangiectasia (p = .015). After multivariate logistic regression, pain (OR: 4.017; 95% CI: 1.198-13.471; p = .024) and color alteration (OR: 7.243; 95% CI: 2.068-25.363; p = .002) were independently associated with malignancy. Including these factors in a predictive index, the proportion of malignant tumors in patients presenting none, one and two factors were 25% (95% CI: 0.13-0.40), 67% (95% CI: 0.48-0.83), and 85% (95% CI: 0.42-0.99), respectively. Pain and color alteration might be independent predictors of malignancy in PSGT, which could support the decision to perform an incisional or excisional biopsy.
Types de publication
Journal Article
Langues
eng
Pagination
1919-1924Subventions
Organisme : Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
ID : Finance code 001
Organisme : Conselho Nacional de Desenvolvimento Científico e Tecnológico
ID : Alan Roger Santos-Silva is a research grantee
Informations de copyright
© 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. All rights reserved.
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