The challenging right inferior pulmonary vein: A systematic approach for successful cryoballoon ablation.

Atrial fibrillation Cryoablation Fibrillation Atriale Isolation veineuse pulmonaire Pulmonary vein isolation Right inferior pulmonary vein Veine pulmonaire inférieure droite

Journal

Archives of cardiovascular diseases
ISSN: 1875-2128
Titre abrégé: Arch Cardiovasc Dis
Pays: Netherlands
ID NLM: 101465655

Informations de publication

Date de publication:
Historique:
received: 20 12 2018
revised: 23 02 2019
accepted: 21 05 2019
pubmed: 27 8 2019
medline: 28 11 2019
entrez: 27 8 2019
Statut: ppublish

Résumé

Pulmonary vein isolation (PVI) using cryoballoon ablation is widely used for rhythm control in patients with paroxysmal atrial fibrillation. This technique has a steep learning curve, and PVI can be achieved quickly in most patients. However, the right inferior pulmonary vein (RIPV) is often challenging to occlude and isolate. We aimed to analyse the efficacy of RIPV ablation using a systematic approach. Consecutive patients referred for cryoballoon ablation of paroxysmal atrial fibrillation were enrolled prospectively. A systematic approach was used for RIPV cryoablation. The primary endpoint was acute RIPV isolation during initial freeze. A total of 214 patients were included. RIPV isolation during initial freeze occurred in 179 patients (82.2%). Real-time PVI could be observed in 72 patients (33.6%), whereas cryoballoon stability required pushing the Achieve™ catheter inside the RIPVs in the remaining patients. The rate of unsuccessful or aborted first freeze as a result of insufficient minimal temperature was significantly higher in patients with real-time pulmonary vein potential recording (16.7% vs. 6.3%; P=0.031). To overcome this issue and obtain both stability and real-time PVI, a dedicated "whip technique" was developed. Twelve patients (5.6%) required a redo ablation; only two of these had a reconnected RIPV. A systematic approach to RIPV cryoablation can lead to a high rate of first freeze application. Operators should not struggle to visualize pulmonary vein potentials before ablation, as this may decrease cryoapplication efficacy. Thus, stability should be preferred over real-time PVI for RIPV ablation. Both stability and real-time PVI can be obtained using a "whip technique".

Sections du résumé

BACKGROUND BACKGROUND
Pulmonary vein isolation (PVI) using cryoballoon ablation is widely used for rhythm control in patients with paroxysmal atrial fibrillation. This technique has a steep learning curve, and PVI can be achieved quickly in most patients. However, the right inferior pulmonary vein (RIPV) is often challenging to occlude and isolate.
AIM OBJECTIVE
We aimed to analyse the efficacy of RIPV ablation using a systematic approach.
METHODS METHODS
Consecutive patients referred for cryoballoon ablation of paroxysmal atrial fibrillation were enrolled prospectively. A systematic approach was used for RIPV cryoablation. The primary endpoint was acute RIPV isolation during initial freeze.
RESULTS RESULTS
A total of 214 patients were included. RIPV isolation during initial freeze occurred in 179 patients (82.2%). Real-time PVI could be observed in 72 patients (33.6%), whereas cryoballoon stability required pushing the Achieve™ catheter inside the RIPVs in the remaining patients. The rate of unsuccessful or aborted first freeze as a result of insufficient minimal temperature was significantly higher in patients with real-time pulmonary vein potential recording (16.7% vs. 6.3%; P=0.031). To overcome this issue and obtain both stability and real-time PVI, a dedicated "whip technique" was developed. Twelve patients (5.6%) required a redo ablation; only two of these had a reconnected RIPV.
CONCLUSIONS CONCLUSIONS
A systematic approach to RIPV cryoablation can lead to a high rate of first freeze application. Operators should not struggle to visualize pulmonary vein potentials before ablation, as this may decrease cryoapplication efficacy. Thus, stability should be preferred over real-time PVI for RIPV ablation. Both stability and real-time PVI can be obtained using a "whip technique".

Identifiants

pubmed: 31447317
pii: S1875-2136(19)30130-5
doi: 10.1016/j.acvd.2019.05.006
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

502-511

Informations de copyright

Copyright © 2019 Elsevier Masson SAS. All rights reserved.

Auteurs

Raphaël P Martins (RP)

Inserm, LTSI-UMR 1099, service de cardiologie et maladies vasculaires, Univ Rennes, CHU de Rennes, 2, rue Henri-Le-Guilloux, 35000 Rennes, France. Electronic address: raphael.martins@chu-rennes.fr.

Amélie Nicolas (A)

Inserm, LTSI-UMR 1099, service de cardiologie et maladies vasculaires, Univ Rennes, CHU de Rennes, 2, rue Henri-Le-Guilloux, 35000 Rennes, France.

Vincent Galand (V)

Inserm, LTSI-UMR 1099, service de cardiologie et maladies vasculaires, Univ Rennes, CHU de Rennes, 2, rue Henri-Le-Guilloux, 35000 Rennes, France.

Camille Pichard (C)

Inserm, LTSI-UMR 1099, service de cardiologie et maladies vasculaires, Univ Rennes, CHU de Rennes, 2, rue Henri-Le-Guilloux, 35000 Rennes, France.

Nathalie Behar (N)

Inserm, LTSI-UMR 1099, service de cardiologie et maladies vasculaires, Univ Rennes, CHU de Rennes, 2, rue Henri-Le-Guilloux, 35000 Rennes, France.

Céline Chérel (C)

Inserm, LTSI-UMR 1099, service de cardiologie et maladies vasculaires, Univ Rennes, CHU de Rennes, 2, rue Henri-Le-Guilloux, 35000 Rennes, France.

Jean-Claude Daubert (JC)

Inserm, LTSI-UMR 1099, service de cardiologie et maladies vasculaires, Univ Rennes, CHU de Rennes, 2, rue Henri-Le-Guilloux, 35000 Rennes, France.

Philippe Mabo (P)

Inserm, LTSI-UMR 1099, service de cardiologie et maladies vasculaires, Univ Rennes, CHU de Rennes, 2, rue Henri-Le-Guilloux, 35000 Rennes, France.

Christophe Leclercq (C)

Inserm, LTSI-UMR 1099, service de cardiologie et maladies vasculaires, Univ Rennes, CHU de Rennes, 2, rue Henri-Le-Guilloux, 35000 Rennes, France.

Mathieu Lederlin (M)

Inserm, LTSI-UMR 1099, service de cardiologie et maladies vasculaires, Univ Rennes, CHU de Rennes, 2, rue Henri-Le-Guilloux, 35000 Rennes, France.

Dominique Pavin (D)

Inserm, LTSI-UMR 1099, service de cardiologie et maladies vasculaires, Univ Rennes, CHU de Rennes, 2, rue Henri-Le-Guilloux, 35000 Rennes, France.

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