Microglia cytoarchitecture in the brain of adenosine A
C57BL/6 mice
dorsal hippocampus
prefrontal cortex
regional dimorphism
sex dimorphism
Journal
The European journal of neuroscience
ISSN: 1460-9568
Titre abrégé: Eur J Neurosci
Pays: France
ID NLM: 8918110
Informations de publication
Date de publication:
03 2020
03 2020
Historique:
received:
12
03
2019
revised:
10
08
2019
accepted:
15
08
2019
pubmed:
28
8
2019
medline:
22
6
2021
entrez:
28
8
2019
Statut:
ppublish
Résumé
Microglia cells exert a critical role in brain development, mainly supported by their immune functions, which predicts an impact on the genesis of psychiatric disorders. In fact, microglia stress during gestation is, for instance, associated with chronic anxiety and cognitive deficits accompanied by long-lasting, region- and sex-specific changes in microglia morphology. We recently reported that the pattern of microglia morphologic plasticity, which is sex-determined, impacts on anxious-like behaviour and cognition. We also reported that the pharmacologic blockade of adenosine A
Substances chimiques
Receptor, Adenosine A2A
0
Adenosine
K72T3FS567
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1377-1387Subventions
Organisme : COMPETE
ID : PTDC/NEU-NMC/4154/2014
Pays : International
Organisme : COMPETE
ID : Project POCI-01-0145-FEDER-007440
Pays : International
Organisme : COMPETE
ID : Strategic project: UID/NEU/04539/2013
Pays : International
Organisme : COMPETE
ID : UID/NEU/04539/2019
Pays : International
Organisme : Santa Casa da Misericórdia, Prémio Maratona da Saúde, and Centro 2020 Regional Operational Programme
ID : CENTRO-01-0145-FEDER-000008: BrainHealth 2020
Pays : International
Organisme : Santa Casa da Misericórdia, Prémio Maratona da Saúde, and Centro 2020 Regional Operational Programme
ID : CENTRO-01-0246-FEDER-000010
Pays : International
Organisme : Portuguese Foundation for Science and Technology
ID : PD/BD/114116/2015
Pays : International
Organisme : Portuguese Foundation for Science and Technology
ID : SFRH/BPD/86830/2012
Pays : International
Informations de copyright
© 2019 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.
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