Antitumor Mechanism of the Essential Oils from Two Succulent Plants in Multidrug Resistance Leukemia Cell.
Cyphostemma juttae
Kalanchoe beharensis
NF-κB
acute myeloid leukemia cell
essential oil
multidrug resistance
Journal
Pharmaceuticals (Basel, Switzerland)
ISSN: 1424-8247
Titre abrégé: Pharmaceuticals (Basel)
Pays: Switzerland
ID NLM: 101238453
Informations de publication
Date de publication:
26 Aug 2019
26 Aug 2019
Historique:
received:
25
07
2019
revised:
16
08
2019
accepted:
23
08
2019
entrez:
29
8
2019
pubmed:
29
8
2019
medline:
29
8
2019
Statut:
epublish
Résumé
Drug resistance remains a major challenge in the treatment of cancer. The multiplicity of the drug resistance determinants raises the question about the optimal strategies to deal with them. Essential oils showed to inhibit the growth of different tumor cell types. Essential oils contain several chemical classes of compounds whose heterogeneity of active moieties can help prevent the development of drug resistance. In the present paper, we analyzed, by gas chromatography-mass spectrometry the chemical composition of the essential oil of the leaves of
Identifiants
pubmed: 31454963
pii: ph12030124
doi: 10.3390/ph12030124
pmc: PMC6789815
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : This work was partially financed by PJ_AUTF_160829_D15 to Monica Notarbartolo.
ID : PJ_AUTF_160829_D15
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