Vascularized pedicle iliac bone grafts as a hip-preserving surgery for femur head necrosis: a systematic review.


Journal

Journal of orthopaedic surgery and research
ISSN: 1749-799X
Titre abrégé: J Orthop Surg Res
Pays: England
ID NLM: 101265112

Informations de publication

Date de publication:
27 Aug 2019
Historique:
received: 19 12 2018
accepted: 08 07 2019
entrez: 29 8 2019
pubmed: 29 8 2019
medline: 11 2 2020
Statut: epublish

Résumé

Osteonecrosis of the femoral head was gradually concerned as a global disease for its progression to collapse of the femoral head, ultimately causing the arthritic change. Due to the high incidence of this disease in young people, arthroplasty tends to be suspected for its uncertain long-term efficiency. Vascularized pedicle iliac bone grafts, as a hip-preserving surgery, were regarded as an effective option in hip-preserving protocol since the 1970s. Nevertheless, there exist no unified standards widely agreed as the optimal operative program since the lack and heterogeneity of related studies. Thus, we execute this systematic review to synthesize and analyze existing studies, and further suggest a direction of future researches. Data were collected by searching electronic database (PubMed, Embase, and Cochrane Library) and including the eligible studies of all types of clinical researches except case report. Through our extraction and synthesis of included study results in respect of clinical evaluation (rating scales), radiographic evaluation, joint survival rate, viability of implanted flap, and complications by transform varied assessment method into a unified standard, we qualitatively analyze and discuss the efficacy of VPIBG according to the quality of individual study and the heterogeneity across the included studies. Our systematic review includes 1 RCT, 2 case-control studies, and 13 case series studies, resulting in a significant improvement of postoperative scores. Minority of hips progressed for joint replacement. Some researches suggested a high collapse rate in the collapsed femoral head before the operation. Compared with some other hip-preserving surgeries, the complications of VPIBG are relatively slight and barely affect clinical efficiency. A better clinic response was obtained after this treatment, especially in femoral heads before the appearance of a crescent sign. The fixation of the implanted iliac bone flap increases the clinical effect. The majority of complications were slight and rarely affected clinical efficacy.

Sections du résumé

BACKGROUND BACKGROUND
Osteonecrosis of the femoral head was gradually concerned as a global disease for its progression to collapse of the femoral head, ultimately causing the arthritic change. Due to the high incidence of this disease in young people, arthroplasty tends to be suspected for its uncertain long-term efficiency. Vascularized pedicle iliac bone grafts, as a hip-preserving surgery, were regarded as an effective option in hip-preserving protocol since the 1970s. Nevertheless, there exist no unified standards widely agreed as the optimal operative program since the lack and heterogeneity of related studies. Thus, we execute this systematic review to synthesize and analyze existing studies, and further suggest a direction of future researches.
METHODS METHODS
Data were collected by searching electronic database (PubMed, Embase, and Cochrane Library) and including the eligible studies of all types of clinical researches except case report. Through our extraction and synthesis of included study results in respect of clinical evaluation (rating scales), radiographic evaluation, joint survival rate, viability of implanted flap, and complications by transform varied assessment method into a unified standard, we qualitatively analyze and discuss the efficacy of VPIBG according to the quality of individual study and the heterogeneity across the included studies.
RESULTS RESULTS
Our systematic review includes 1 RCT, 2 case-control studies, and 13 case series studies, resulting in a significant improvement of postoperative scores. Minority of hips progressed for joint replacement. Some researches suggested a high collapse rate in the collapsed femoral head before the operation. Compared with some other hip-preserving surgeries, the complications of VPIBG are relatively slight and barely affect clinical efficiency.
CONCLUSIONS CONCLUSIONS
A better clinic response was obtained after this treatment, especially in femoral heads before the appearance of a crescent sign. The fixation of the implanted iliac bone flap increases the clinical effect. The majority of complications were slight and rarely affected clinical efficacy.

Identifiants

pubmed: 31455329
doi: 10.1186/s13018-019-1262-2
pii: 10.1186/s13018-019-1262-2
pmc: PMC6710879
doi:

Types de publication

Journal Article Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

270

Subventions

Organisme : National Natural Science Foundation of China
ID : 81473697
Organisme : National Natural Science Foundation of China
ID : 81573996
Organisme : the science and technology plan project of Guangdong province
ID : 2016A020226028
Organisme : Natural Science Foundation of Guangdong Province
ID : 2017A030313698
Organisme : Special Construction Project of Dominant Disease (ONFH) of Chinese Medicine in Guangdong Province
ID : [2015]19
Organisme : Inheritance Studio Construction Project of Prestigious TCM Doctors (He Wei) in Guangdong Province
ID : [2017]17

Références

Clin Orthop Relat Res. 2001 May;(386):100-5
pubmed: 11347821
J Bone Joint Surg Br. 2003 Mar;85(2):191-8
pubmed: 12678351
Clin Orthop Relat Res. 2003 Jul;(412):84-93
pubmed: 12838057
Arch Orthop Trauma Surg. 2005 Mar;125(2):95-101
pubmed: 15657765
Aliment Pharmacol Ther. 2005 Feb 1;21(3):243-9
pubmed: 15691298
J Reconstr Microsurg. 2005 Feb;21(2):101-5
pubmed: 15739145
N Engl J Med. 1992 May 28;326(22):1473-9
pubmed: 1574093
J Orthop Sci. 2004;9(6):566-70
pubmed: 16228672
Clin Orthop Relat Res. 2006 Jan;442:171-9
pubmed: 16394757
J Reconstr Microsurg. 2006 Jan;22(1):21-4
pubmed: 16425117
J Bone Joint Surg Am. 2006 Nov;88 Suppl 3:16-26
pubmed: 17079363
Int Orthop. 2009 Feb;33(1):41-7
pubmed: 17992527
J Clin Epidemiol. 2009 Oct;62(10):e1-34
pubmed: 19631507
J Arthroplasty. 2009 Dec;24(8):1178-83
pubmed: 19640674
Indian J Orthop. 2009 Jan;43(1):27-35
pubmed: 19753176
J Bone Joint Surg Am. 2009 Oct;91(10):2390-4
pubmed: 19797574
Clin Orthop Relat Res. 2010 May;468(5):1316-24
pubmed: 19898910
Int J Surg. 2010;8(5):336-41
pubmed: 20171303
J Orthop Sci. 2010 Jul;15(4):452-8
pubmed: 20721711
Clin Orthop Relat Res. 2012 Feb;470(2):525-34
pubmed: 21879405
Ann Oncol. 2012 May;23(5):1254-9
pubmed: 21926399
Rom J Morphol Embryol. 2012;53(3 Suppl):763-7
pubmed: 23188437
Int Orthop. 2013 Mar;37(3):391-8
pubmed: 23340673
Orthopedics. 2013 Jun;36(6):789-95
pubmed: 23746017
Eklem Hastalik Cerrahisi. 2014;25(1):2-7
pubmed: 24650377
Mod Rheumatol. 2015 Mar;25(2):278-81
pubmed: 25036228
J Chiropr Med. 2014 Sep;13(3):196-202
pubmed: 25225469
J Bone Joint Surg Am. 2014 Nov 5;96(21):1814-9
pubmed: 25378509
Int J Dent Hyg. 2016 Feb;14(1):62-73
pubmed: 25690049
Curr Rev Musculoskelet Med. 2015 Sep;8(3):252-9
pubmed: 26068178
Int J Clin Exp Med. 2015 Apr 15;8(4):5207-16
pubmed: 26131094
Int Orthop. 2016 Jul;40(7):1417-25
pubmed: 26174057
J Clin Epidemiol. 2016 Jan;69:199-207.e2
pubmed: 26307459
J Chin Med Assoc. 2016 Jan;79(1):39-45
pubmed: 26387635
J Bone Joint Surg Am. 2015 Oct 7;97(19):1604-27
pubmed: 26446969
Biomaterials. 2016 Mar;81:84-92
pubmed: 26724456
J Bone Joint Surg Am. 1974 Mar;56(2):273-84
pubmed: 4452686
J Bone Joint Surg Am. 1971 Dec;53(8):1645-7
pubmed: 4941381
J Bone Joint Surg Am. 1995 Mar;77(3):459-74
pubmed: 7890797
Clin Orthop Relat Res. 1993 Oct;(295):281-8
pubmed: 8403663
Clin Orthop Relat Res. 1996 Feb;(323):139-45
pubmed: 8625571
Radiographics. 1996 May;16(3):585-94
pubmed: 8897626
Clin Orthop Relat Res. 1997 Apr;(337):140-8
pubmed: 9137185
Arch Orthop Trauma Surg. 1997;116(5):251-8
pubmed: 9177798

Auteurs

Fan Yang (F)

The First Clinical Medical School, Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong, China.

Qiushi Wei (Q)

Institute of Hip Joint, First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.

Xiaojun Chen (X)

The First Clinical Medical School, Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong, China.

Guoju Hong (G)

The First Clinical Medical School, Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong, China.

Zhenqiu Chen (Z)

Institute of Hip Joint, First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.

Yaolong Chen (Y)

Key Laboratory of Evidence Based Medicine of Lanzhou University, Lanzhou, Gansu, China.

Wei He (W)

Institute of Hip Joint, First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China. hw13802516062@163.com.

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