Highly Sensitive Detection of Uracil-DNA Glycosylase Activity Based on Self-Initiating Multiple Rolling Circle Amplification.
Journal
ACS omega
ISSN: 2470-1343
Titre abrégé: ACS Omega
Pays: United States
ID NLM: 101691658
Informations de publication
Date de publication:
28 Feb 2019
28 Feb 2019
Historique:
received:
02
12
2018
accepted:
08
02
2019
entrez:
29
8
2019
pubmed:
29
8
2019
medline:
29
8
2019
Statut:
epublish
Résumé
Sensitive detection of uracil-DNA glycosylase (UDG) activity is very important in the study of many fundamental biochemical processes and clinical applications. Here, we develop a novel assay for the detection of UDG activity by using the self-initiating multiple rolling circle amplification (SM-RCA) strategy. We first design a trigger probe modified with NH
Identifiants
pubmed: 31459598
doi: 10.1021/acsomega.8b03376
pmc: PMC6648713
doi:
Types de publication
Journal Article
Langues
eng
Pagination
3881-3886Déclaration de conflit d'intérêts
The authors declare no competing financial interest.
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