Prevalence and causes of vision loss in East Asia in 2015: magnitude, temporal trends and projections.

Blindness / epidemiology Asia, Eastern / epidemiology Humans Prevalence Visual Acuity

blindness cataract glaucoma global burden of disease study macular degeneration, epidemiology refractive error vision impairment vision loss vision loss expert group

Journal

The British journal of ophthalmology

ISSN: 1468-2079

Titre abrégé: Br J Ophthalmol

Pays: England

ID NLM: 0421041

Informations de publication

Date de publication:
05 2020

Historique:

received: 02 10 2018

revised: 21 07 2019

accepted: 11 08 2019

pubmed: 30 8 2019

medline: 23 12 2020

entrez: 30 8 2019

Statut: ppublish

Résumé

To determine the prevalence and causes of blindness and vision impairment (VI) in East Asia in 2015 and to forecast the trend to 2020. Through a systematic literature review and meta-analysis, we estimated prevalence of blindness (presenting visual acuity <3/60 in the better eye), moderate-to-severe vision impairment (MSVI; 3/60≤presenting visual acuity <6/18), mild vision impairment (mild VI: 6/18≤presenting visual acuity <6/12) and uncorrected presbyopia for 1990, 2010, 2015 and 2020. A total of 44 population-based studies were included. In 2015, age-standardised prevalence of blindness, MSVI, mild VI and uncorrected presbyopia was 0.37% (80% uncertainty interval (UI) 0.12%-0.68%), 3.06% (80% UI 1.35%-5.16%) and 2.65% (80% UI 0.92%-4.91%), 32.91% (80% UI 18.72%-48.47%), respectively, in East Asia. Cataract was the leading cause of blindness (43.6%), followed by uncorrected refractive error (12.9%), glaucoma, age-related macular degeneration, corneal diseases, trachoma and diabetic retinopathy (DR). The leading cause for MSVI was uncorrected refractive error, followed by cataract, age-related macular degeneration, glaucoma, corneal disease, trachoma and DR. The burden of VI due to uncorrected refractive error, cataracts, glaucoma and DR has continued to rise over the decades reported. Addressing the public healthcare barriers for cataract and uncorrected refractive error can help eliminate almost 57% of all blindness cases in this region. Therefore, public healthcare efforts should be focused on effective screening and effective patient education, with access to high-quality healthcare.

Sections du résumé

BACKGROUND

To determine the prevalence and causes of blindness and vision impairment (VI) in East Asia in 2015 and to forecast the trend to 2020.

METHODS

Through a systematic literature review and meta-analysis, we estimated prevalence of blindness (presenting visual acuity <3/60 in the better eye), moderate-to-severe vision impairment (MSVI; 3/60≤presenting visual acuity <6/18), mild vision impairment (mild VI: 6/18≤presenting visual acuity <6/12) and uncorrected presbyopia for 1990, 2010, 2015 and 2020. A total of 44 population-based studies were included.

RESULTS

In 2015, age-standardised prevalence of blindness, MSVI, mild VI and uncorrected presbyopia was 0.37% (80% uncertainty interval (UI) 0.12%-0.68%), 3.06% (80% UI 1.35%-5.16%) and 2.65% (80% UI 0.92%-4.91%), 32.91% (80% UI 18.72%-48.47%), respectively, in East Asia. Cataract was the leading cause of blindness (43.6%), followed by uncorrected refractive error (12.9%), glaucoma, age-related macular degeneration, corneal diseases, trachoma and diabetic retinopathy (DR). The leading cause for MSVI was uncorrected refractive error, followed by cataract, age-related macular degeneration, glaucoma, corneal disease, trachoma and DR. The burden of VI due to uncorrected refractive error, cataracts, glaucoma and DR has continued to rise over the decades reported.

CONCLUSIONS

Addressing the public healthcare barriers for cataract and uncorrected refractive error can help eliminate almost 57% of all blindness cases in this region. Therefore, public healthcare efforts should be focused on effective screening and effective patient education, with access to high-quality healthcare.

Identifiants

DOI: 10.1136/bjophthalmol-2018-313308 PMID: 31462416

pubmed: 31462416

pii: bjophthalmol-2018-313308

doi: 10.1136/bjophthalmol-2018-313308

doi:

Types de publication

Journal Article Meta-Analysis Research Support, Non-U.S. Gov't Systematic Review

Langues

eng

Sous-ensembles de citation

Pagination

616-622

Investigateurs

Rupert Bourne (R)

Peter Ackland (P)

Aries Arditi (A)

Yaniv Barkana (Y)

Banu Bozkurt (B)

Tasanee Braithwaite (T)

Alain Bron (A)

Donald Budenz (D)

Feng Cai (F)

Robert Casson (R)

Usha Chakravarthy (U)

Jaewan Choi (J)

Maria Vittoria Cicinelli (MV)

Nathan Congdon (N)

Reza Dana (R)

Rakhi Dandona (R)

Lalit Dandona (L)

Aditi Das (A)

Iva Dekaris (I)

Monte Del Monte (MD)

Jenny Deva (J)

Mohamed Dirani (M)

Laura Dreer (L)

Leon Ellwein (L)

Marcela Frazier (M)

Kevin Frick (K)

David Friedman (D)

Joao Furtado (J)

Hua Gao (H)

Andrew Gazzard (A)

Ronnie George (R)

Stephen Gichuhi (S)

Victor Gonzalez (V)

Billy Hammond (B)

Mary Elizabeth Hartnett (ME)

Minguang He (M)

James Hejtmancik (J)

Flavio Hirai (F)

John Huang (J)

April Ingram (A)

Jonathan Javitt (J)

Jost Jonas (J)

Charlotte Joslin (C)

Jill Keeffe (J)

John Kempen (J)

Moncef Khairallah (M)

Rohit Khanna (R)

Judy Kim (J)

George Lambrou (G)

Van Charles Lansingh (VC)

Paolo Lanzetta (P)

Janet Leasher (J)

Jennifer Lim (J)

Hans Limburg (H)

Kaweh Mansouri (K)

Anu Mathew (A)

Alan Morse (A)

Beatriz Munoz (B)

David Musch (D)

Kovin Naidoo (K)

Vinay Nangia (V)

Maria Palaiou (M)

Maurizio Battaglia Parodi (MB)

Fernando Yaacov Pena (FY)

Konrad Pesudovs (K)

Tunde Peto (T)

Harry Quigley (H)

Murugesan Raju (M)

Pradeep Ramulu (P)

Serge Resnikoff (S)

Dana Reza (D)

Alan Robin (A)

Luca Rossetti (L)

Jinan Saaddine (J)

Mya Sandar (M)

Janet Serle (J)

Tueng Shen (T)

Rajesh Shetty (R)

Pamela Sieving (P)

Juan Carlos Silva (JC)

Alex Silvester (A)

Rita S Sitorus (RS)

Dwight Stambolian (D)

Gretchen Stevens (G)

Hugh Taylor (H)

Jaime Tejedor (J)

James Tielsch (J)

Fotis Topouzis (F)

Miltiadis Tsilimbaris (M)

Jan van Meurs (JV)

Rohit Varma (R)

Gianni Virgili (G)

Jimmy Volmink (J)

Ya Xing Wang (YX)

Ning-Li Wang (NL)

Peter Wiedemann (P)

Tien Wong (T)

Richard Wormald (R)

Yingfeng Zheng (Y)

Sheila West (S)

Informations de copyright

Déclaration de conflit d'intérêts

Competing interests: JBJ: Consultant for Mundipharma Co. (Cambridge, UK); Patent holder with Biocompatibles UK Ltd. (Farnham, Surrey, UK) (Title: Treatment of eye diseases using encapsulated cells encoding and secreting neuroprotective factor and/or anti-angiogenic factor; Patent number: 20120263794), and Patent application with University of Heidelberg (Heidelberg, Germany) (Title: Agents for use in the therapeutic or prophylactic treatment of myopia or hyperopia; Europäische Patentanmeldung 15 000 771.4). JHK: consultant for Gilead (DSMC Chair), Santen (protocol design). SR: consultant for Brien Holden Vision Institute.