A multicentric cross-sectional study to characterize the scale and impact of polypharmacy in rural Indian communities, conducted as part of health workers training.

Drug interactions India medication errors polypharmacy prescription public health rural communities rural health survey

Journal

Journal of family medicine and primary care
ISSN: 2249-4863
Titre abrégé: J Family Med Prim Care
Pays: India
ID NLM: 101610082

Informations de publication

Date de publication:
Jul 2019
Historique:
entrez: 30 8 2019
pubmed: 30 8 2019
medline: 30 8 2019
Statut: ppublish

Résumé

Polypharmacy and inappropriate medication usage is one of the world's most important public health issues. Yet in rural India, where medications are readily available, little is known about polypharmacy. This study explores factors related to polypharmacy in rural India to inform the response. A household survey was conducted by community health trainees, across 515 Indian villages collecting medication prescription and usage information for single illness in the past month. Polypharmacy was defined as the concurrent usage of four or more medications for single illness. Data from 515 rural India villages were collected on medication usage for their last illness. Respondents who consulted one healthcare provider for this illness were included for analysis. Bivariate logistic regression and multivariate generalized estimating equation analysis were used to explore associations with polypharmacy. Prevalence of polypharmacy was 13% ( The study demonstrates high rates of polypharmacy, identifies vulnerable populations, and provides information to improve the response to polypharmacy in rural India.

Identifiants

pubmed: 31463236
doi: 10.4103/jfmpc.jfmpc_410_19
pii: JFMPC-8-2234
pmc: PMC6691404
doi:

Types de publication

Journal Article

Langues

eng

Pagination

2234-2241

Déclaration de conflit d'intérêts

There are no conflicts of interest.

Références

J Gen Intern Med. 2007 May;22(5):685-91
pubmed: 17443380
Fundam Clin Pharmacol. 2013 Apr;27(2):231-7
pubmed: 21895763
Int J Chron Obstruct Pulmon Dis. 2011;6:493-501
pubmed: 22069360
Health Aff (Millwood). 2012 Dec;31(12):2774-84
pubmed: 23213162
Scand J Trauma Resusc Emerg Med. 2013 Mar 05;21:15
pubmed: 23497667
PLoS One. 2013 Dec 20;8(12):e84967
pubmed: 24376858
PLoS One. 2015 May 12;10(5):e0125865
pubmed: 25965382
J Public Health (Oxf). 2016 Jun;38(2):e150-7
pubmed: 26060236
Indian J Med Res. 2015 May;141(5):537-45
pubmed: 26139770
BMJ Open. 2015 Sep 18;5(9):e008656
pubmed: 26384726
JAMA. 2015 Nov 3;314(17):1818-31
pubmed: 26529160
Lancet. 2015 Dec 12;386(10011):2422-35
pubmed: 26700532
Prev Med Rep. 2014 Oct 22;1:43-7
pubmed: 26844038
PLoS Med. 2016 Mar 02;13(3):e1001974
pubmed: 26934098
J Clin Diagn Res. 2016 Feb;10(2):FC06-10
pubmed: 27042480
J Pharmacol Pharmacother. 2016 Jan-Mar;7(1):1-5
pubmed: 27127387
Age Ageing. 2016 Jul;45(4):535-42
pubmed: 27151390
Rev Lat Am Enfermagem. 2016 Sep 01;24:e2800
pubmed: 27598380
Implement Sci. 2017 Mar 6;12(1):31
pubmed: 28264693
Indian J Pharmacol. 2017 Jan-Feb;49(1):16-20
pubmed: 28458417
PLoS One. 2017 Aug 22;12(8):e0183461
pubmed: 28829812
Age Ageing. 2017 Nov 1;46(6):882-888
pubmed: 28985248
Global Health. 2018 Apr 13;14(1):34
pubmed: 29653547
PLoS One. 2018 Apr 18;13(4):e0195232
pubmed: 29668763
BMC Med. 2018 Jun 13;16(1):91
pubmed: 29895310
Drugs Aging. 2018 Jul;35(7):575-587
pubmed: 30006810
Clin Interv Aging. 2018 Oct 15;13:2003-2011
pubmed: 30410317
PLoS One. 2018 Dec 5;13(12):e0207511
pubmed: 30517130
Int J Environ Res Public Health. 2019 Mar 06;16(5):
pubmed: 30845721
BMJ. 1997 Aug 30;315(7107):520-3
pubmed: 9329308

Auteurs

Sangeetha Balaji (S)

Department of Distance Education Unit, Christian Medical College, Vellore, Tamil Nadu, India.

Monsurul Hoq (M)

Clinical Epidemiology and Biostatistics Unit, Murdoch Children's Research Institute, Victoria, Australia.

Jachin Velavan (J)

Department of Distance Education Unit, Christian Medical College, Vellore, Tamil Nadu, India.

Beulah Raji (B)

Department of Distance Education Unit, Christian Medical College, Vellore, Tamil Nadu, India.

Eva Grace (E)

Department of Distance Education Unit, Christian Medical College, Vellore, Tamil Nadu, India.

Sara Bhattacharji (S)

Department of Distance Education Unit, Christian Medical College, Vellore, Tamil Nadu, India.

Nathan Grills (N)

Australia India Institute and Nossal Institute for Global Health, The University of Melbourne, Australia.

Classifications MeSH