Human keratinocyte carcinomas have distinct differences in their tumor-associated macrophages.
BCC
Basal cell carcinoma
Cancer research
Cell differentiation
Immune response
Immunology
Lactic acid
Macrophage polarization and density
SCC
Squamous cell carcinoma
TAMs
Tumor-associated macrophages
Journal
Heliyon
ISSN: 2405-8440
Titre abrégé: Heliyon
Pays: England
ID NLM: 101672560
Informations de publication
Date de publication:
Aug 2019
Aug 2019
Historique:
received:
17
11
2018
revised:
11
06
2019
accepted:
06
08
2019
entrez:
30
8
2019
pubmed:
30
8
2019
medline:
30
8
2019
Statut:
epublish
Résumé
Cutaneous squamous cell carcinomas (SCCs) and basal cell carcinomas (BCCs) have different clinical behaviors, despite both being keratinocyte carcinomas mainly caused by ultraviolet radiation. Whether these distinct features are associated with tumor-associated macrophages (TAMs) is largely unknown. The main goal of this study was to conduct a comprehensive analysis of density and polarization states of TAMs in SCCs Few studies have studied tumor-associated macrophages in the context of SCC
Identifiants
pubmed: 31463392
doi: 10.1016/j.heliyon.2019.e02273
pii: S2405-8440(19)35933-X
pii: e02273
pmc: PMC6706589
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e02273Subventions
Organisme : NIGMS NIH HHS
ID : T32 GM007205
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001863
Pays : United States
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