Correlation of Quantitated Intravascular Volume with Blood Pressure in Patients with Systemic Hypertension.
Blood volume analysis
Gender
Hypertension
Race
Journal
Journal of cardiovascular translational research
ISSN: 1937-5395
Titre abrégé: J Cardiovasc Transl Res
Pays: United States
ID NLM: 101468585
Informations de publication
Date de publication:
08 2020
08 2020
Historique:
received:
12
07
2019
accepted:
23
08
2019
pubmed:
30
8
2019
medline:
2
12
2020
entrez:
30
8
2019
Statut:
ppublish
Résumé
Volume management is an essential component of anti-hypertensive therapy. Different volume phenotypes have been proposed. We sought to study the total blood volume (TBV), plasma volume (PV), and red blood cell volume (RBV) in hypertensive patients. We included patients followed in an outpatient cardiology clinic from 1998 to 2003. Blood volume (BV) parameters were measured using radioisotope iodine-131-labeled albumin dilution technique. Values were expressed as percentage (%) deviation from ideal volumes. A total of 95 patients were included. The intravascular volume distribution as percent deviation from normal volume ranged from - 23 to + 28% for TBV, - 22 to + 36% for PV and - 29 to + 37% for RBV. There was no significant correlation between systolic BP and any of the BV parameters (TBV and SBP, r = - 0.03; PV and SBP, r = - 0.12; RBV and SBP, r = - 0.08). Patients with hypertension have a wide variation in BV parameters. BV does not correlate with SBP.
Identifiants
pubmed: 31463701
doi: 10.1007/s12265-019-09910-4
pii: 10.1007/s12265-019-09910-4
pmc: PMC8034589
mid: NIHMS1687322
doi:
Substances chimiques
Serum Albumin, Radio-Iodinated
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
528-530Subventions
Organisme : NHLBI NIH HHS
ID : T32 HL007101
Pays : United States
Références
Heart. 2003 Sep;89(9):1104-9
pubmed: 12923045
Am J Med Sci. 2007 Jul;334(1):41-6
pubmed: 17630591
Circulation. 1977 Oct;56(4 Pt 1):605-12
pubmed: 902387
Hypertension. 1979 Mar-Apr;1(2):136-41
pubmed: 399939
Fed Proc. 1982 Jun;41(8):2415-23
pubmed: 7084486
Am J Med. 1977 Feb;62(2):209-18
pubmed: 835600