Underutilization of potential donors for lung transplantation at a tertiary care center in North India.
Brain death
end-stage lung disease
lung allocation
lung donation
lung transplantation
Journal
Lung India : official organ of Indian Chest Society
ISSN: 0970-2113
Titre abrégé: Lung India
Pays: India
ID NLM: 8405380
Informations de publication
Date de publication:
Historique:
entrez:
30
8
2019
pubmed:
30
8
2019
medline:
30
8
2019
Statut:
ppublish
Résumé
Lung transplantation is infrequently performed in India due to several constraints, and whether the poor lung transplantation rates in India are due to a lack of eligible lung donors is unclear. In this study, we explored the availability of donors for lung transplantation. This was a retrospective analysis of all brain-dead participants who underwent assessment of eligibility for lung donation between August 2015 and June 2018. All participants underwent a detailed clinical evaluation that included history, physical examination, arterial blood gas analysis, chest radiograph, and bronchoscopy. The final eligibility for lung donation was assessed using the existing "ideal" criteria and the less stringent "extended" criteria. A total of 55 brain-dead participants (41 [74.5%] males) were assessed for eligibility for lung donation. The mean (standard deviation [SD]) age of the participants was 38.4 (17.2) years. The mean (SD) duration of prior invasive mechanical ventilation at the time of assessment was 4 (3.1) days, with a mean (SD) partial pressure of arterial oxygen: inspired oxygen fraction ratio (PaO Even with the most stringent criteria for lung assessment, nearly one-third of the brain-dead participants had lungs suitable for lung transplantation. Lack of eligible lung donors is not a reason for the poor lung transplantation rates in India.
Identifiants
pubmed: 31464211
pii: LungIndia_2019_36_5_399_265170
doi: 10.4103/lungindia.lungindia_299_18
pmc: PMC6710964
doi:
Types de publication
Journal Article
Langues
eng
Pagination
399-403Déclaration de conflit d'intérêts
None
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