Chitosan and Quercetin: Potential Hand in Hand Encountering Tumors in Oral Delivery System.
Chitosan
cancer therapy
crosslinking
drug delivery system
interaction
polymer
quercetin.
Journal
Current pharmaceutical design
ISSN: 1873-4286
Titre abrégé: Curr Pharm Des
Pays: United Arab Emirates
ID NLM: 9602487
Informations de publication
Date de publication:
2019
2019
Historique:
received:
11
05
2019
accepted:
21
08
2019
pubmed:
30
8
2019
medline:
2
6
2020
entrez:
30
8
2019
Statut:
ppublish
Résumé
Chitosan is a cationic polysaccharide and multi-potential polymer with the ability to interact with other natural and synthetic polyanionic/polymeric compounds, with or without a cross-linking agent. It has been able to composite nano-microparticles with a variety of features. This compound has the ability to carry quercetin, as an anti-tumor subject, through the various epithelial systems and release in the sustained and controlled state to the target site. This paper reviews published studies on detailed physicochemical properties of chitosan and quercetin in the fight against the tumor. This also focused on how the chitosan polymer interacts with other polymeric and polyanion species in order to improve its efficiency to make a more suitable capsule or matrix for a variety of drugs, especially quercetin, in oral delivery systems.
Identifiants
pubmed: 31465272
pii: CPD-EPUB-100519
doi: 10.2174/1381612825666190829144508
doi:
Substances chimiques
Chitosan
9012-76-4
Quercetin
9IKM0I5T1E
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
3074-3086Informations de copyright
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