Validation of algorithmic CT image quality metrics with preferences of radiologists.

CT image quality automated assessment clinical images diagnostic reference level observer study validation of algorithmic metrics

Journal

Medical physics
ISSN: 2473-4209
Titre abrégé: Med Phys
Pays: United States
ID NLM: 0425746

Informations de publication

Date de publication:
Nov 2019
Historique:
received: 18 04 2019
revised: 13 08 2019
accepted: 13 08 2019
pubmed: 30 8 2019
medline: 20 3 2020
entrez: 30 8 2019
Statut: ppublish

Résumé

Automated assessment of perceptual image quality on clinical Computed Tomography (CT) data by computer algorithms has the potential to greatly facilitate data-driven monitoring and optimization of CT image acquisition protocols. The application of these techniques in clinical operation requires the knowledge of how the output of the computer algorithms corresponds to clinical expectations. This study addressed the need to validate algorithmic image quality measurements on clinical CT images with preferences of radiologists and determine the clinically acceptable range of algorithmic measurements for abdominal CT examinations. Algorithmic measurements of image quality metrics (organ HU, noise magnitude, and clarity) were performed on a clinical CT image dataset with supplemental measures of noise power spectrum from phantom images using techniques developed previously. The algorithmic measurements were compared to clinical expectations of image quality in an observer study with seven radiologists. Sets of CT liver images were selected from the dataset where images in the same set varied in terms of one metric at a time. These sets of images were shown via a web interface to one observer at a time. First, the observer rank ordered the CT images in a set according to his/her preference for the varying metric. The observer then selected his/her preferred acceptable range of the metric within the ranked images. The agreement between algorithmic and observer rankings of image quality were investigated and the clinically acceptable image quality in terms of algorithmic measurements were determined. The overall rank-order agreements between algorithmic and observer assessments were 0.90, 0.98, and 1.00 for noise magnitude, liver parenchyma HU, and clarity, respectively. The results indicate a strong agreement between the algorithmic and observer assessments of image quality. Clinically acceptable thresholds (median) of algorithmic metric values were (17.8, 32.6) HU for noise magnitude, (92.1, 131.9) for liver parenchyma HU, and (0.47, 0.52) for clarity. The observer study results indicated that these algorithms can robustly assess the perceptual quality of clinical CT images in an automated fashion. Clinically acceptable ranges of algorithmic measurements were determined. The correspondence of these image quality assessment algorithms to clinical expectations paves the way toward establishing diagnostic reference levels in terms of clinically acceptable perceptual image quality and data-driven optimization of CT image acquisition protocols.

Identifiants

pubmed: 31465538
doi: 10.1002/mp.13795
doi:

Types de publication

Journal Article Validation Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

4837-4846

Subventions

Organisme : Siemens Healthineers

Informations de copyright

© 2019 American Association of Physicists in Medicine.

Références

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Auteurs

Yuan Cheng (Y)

Clinical Imaging Physics Group, Medical Physics Graduate Program, Carl E. Ravin Advanced Imaging Laboratories, Duke University, 2424 Erwin Rd, Suite 302, Durham, NC, 27705, USA.

Ehsan Abadi (E)

Carl E. Ravin Advanced Imaging Labs and Clinical Imaging Physics Group, Duke University Health System, 2424 Erwin Road, Suite 302, Durham, NC, 27710, USA.
Department of Radiology, Duke University Health System, Box 3808, Room 1531, Erwin Rd, Durham, NC, 27710, USA.

Taylor Brunton Smith (TB)

Clinical Imaging Physics Group, Medical Physics Graduate Program, Carl E. Ravin Advanced Imaging Laboratories, Duke University, 2424 Erwin Rd, Suite 302, Durham, NC, 27705, USA.

Francesco Ria (F)

Carl E. Ravin Advanced Imaging Labs and Clinical Imaging Physics Group, Duke University Health System, 2424 Erwin Road, Suite 302, Durham, NC, 27710, USA.

Mathias Meyer (M)

Department of Radiology, Duke University Health System, Box 3808, Room 1531, Erwin Rd, Durham, NC, 27710, USA.

Daniele Marin (D)

Department of Radiology, Duke University Health System, Box 3808, Room 1531, Erwin Rd, Durham, NC, 27710, USA.

Ehsan Samei (E)

Clinical Imaging Physics Group, Medical Physics Graduate Program, Carl E. Ravin Advanced Imaging Laboratories, Departments of Radiology, Physics, Biomedical Engineering, and Electrical and Computer Engineering, Duke University, 2424 Erwin Rd, Suite 302, Durham, NC, 27705, USA.

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