Humoral Immune Deficiencies of Childhood.

Agammaglobulinemia / immunology Antibody Formation / immunology Child Child, Preschool Humans Immunity, Humoral Immunoglobulins / deficiency Immunologic Deficiency Syndromes / immunology Infant Infant, Newborn
Antibody deficiency B cell deficiency Humoral immune deficiency Immunoglobulin deficiency

Journal

Pediatric clinics of North America
ISSN: 1557-8240
Titre abrégé: Pediatr Clin North Am
Pays: United States
ID NLM: 0401126

Informations de publication

Date de publication:
10 2019
Historique:
entrez: 31 8 2019
pubmed: 31 8 2019
medline: 24 1 2020
Statut: ppublish

Résumé

The most common primary immune deficiencies are those of the humoral immune system, and most of these present in childhood. The severity of these disorders ranges from transient deficiencies to deficiencies that are associated with a complete loss of ability to make adequate or functional antibodies, and have infectious as well as noninfectious complications. This article reviews, in a case-based discussion, the most common of the humoral immune deficiencies; their presentations, diagnoses, treatments; and, when known, the genetic defects.

Identifiants

DOI: 10.1016/j.pcl.2019.06.010 PMID: 31466679
pubmed: 31466679
pii: S0031-3955(19)30092-6
doi: 10.1016/j.pcl.2019.06.010
pii:
doi:

Substances chimiques

Immunoglobulins 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

897-903

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Marwa El-Bohy (M)

Division of Allergy and Immunology, Department of Pediatrics, Children's Hospital of Michigan, Wayne State University, 3950 Beaubien Boulevard, Detroit, MI 48201, USA.

Pavadee Poowuttikul (P)

Division of Allergy and Immunology, Department of Pediatrics, Children's Hospital of Michigan, Wayne State University, 3950 Beaubien Boulevard, Detroit, MI 48201, USA.

Elizabeth Secord (E)

Division of Allergy and Immunology, Department of Pediatrics, Children's Hospital of Michigan, Wayne State University, 3950 Beaubien Boulevard, Detroit, MI 48201, USA. Electronic address: esecord@med.wayne.edu.

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Classifications MeSH

questionsmedicales.fr › Maladies du système immunitaire › Déficits immunitaires › Agammaglobulinémie › Humoral Immune Deficiencies of Childhood.
questionsmedicales.fr › Phénomènes du système immunitaire › Immunité › Immunité acquise › Immunité active › Production d'anticorps › Humoral Immune Deficiencies of Childhood.
questionsmedicales.fr › Personnes › Tranches d'âge › Enfant › Humoral Immune Deficiencies of Childhood.
questionsmedicales.fr › Personnes › Tranches d'âge › Enfant › Enfant d'âge préscolaire › Humoral Immune Deficiencies of Childhood.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Humoral Immune Deficiencies of Childhood.
questionsmedicales.fr › Phénomènes du système immunitaire › Immunité › Immunité acquise › Immunité humorale › Humoral Immune Deficiencies of Childhood.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Humoral Immune Deficiencies of Childhood.
questionsmedicales.fr › Maladies du système immunitaire › Déficits immunitaires › Humoral Immune Deficiencies of Childhood.
questionsmedicales.fr › Personnes › Tranches d'âge › Nourrisson › Humoral Immune Deficiencies of Childhood.
questionsmedicales.fr › Personnes › Tranches d'âge › Nourrisson › Nouveau-né › Humoral Immune Deficiencies of Childhood.