Xanthone, benzophenone and bianthrone derivatives from the hypersaline lake-derived fungus Aspergillus wentii.
Aspergillus wentii
Bianthrone
DFT-based quantum chemical calculations
Structure elucidation
Journal
Bioorganic & medicinal chemistry
ISSN: 1464-3391
Titre abrégé: Bioorg Med Chem
Pays: England
ID NLM: 9413298
Informations de publication
Date de publication:
15 10 2019
15 10 2019
Historique:
received:
08
06
2019
accepted:
10
07
2019
pubmed:
31
8
2019
medline:
22
10
2020
entrez:
31
8
2019
Statut:
ppublish
Résumé
Five new metabolites, including the xanthone derivative wentixanthone A (1), the benzophenone wentiphenone A (2), the diastereomeric mixtures of the bianthrones wentibianthrone A (3a, b) and wentibianthrone B (4a, b), as well as (10R,10'S)-wentibianthrone C (5a) and (10R,10'R)-wentibianthrone C (5b) were obtained from the fungus Aspergillus wentii, isolated from soil of the hypersaline lake El Hamra in Wadi El-Natrun, Egypt. The structures of the isolated compounds were established by one and two-dimensional NMR and MS spectroscopic analysis. The relative configuration of bianthrones (3-5) was elucidated by comparison of experimental and computed
Identifiants
pubmed: 31466836
pii: S0968-0896(19)30776-X
doi: 10.1016/j.bmc.2019.07.021
pii:
doi:
Substances chimiques
Anthracenes
0
Benzophenones
0
Xanthones
0
bianthrone
434-85-5
benzophenone
701M4TTV9O
xanthone
9749WEV0CA
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
115005Informations de copyright
Copyright © 2019. Published by Elsevier Ltd.