Simple liver cysts and cystoid lesions in hepatic alveolar echinococcosis: a retrospective cohort study with Hounsfield analysis.
Kystes hépatiques simples et lésions cystoïdes dans l’échinococcose alvéolaire hépatique : une étude de cohorte rétrospective avec analyse de Hounsfield.
Journal
Parasite (Paris, France)
ISSN: 1776-1042
Titre abrégé: Parasite
Pays: France
ID NLM: 9437094
Informations de publication
Date de publication:
2019
2019
Historique:
received:
14
05
2019
accepted:
15
08
2019
entrez:
31
8
2019
pubmed:
31
8
2019
medline:
20
12
2019
Statut:
ppublish
Résumé
Alveolar echinococcosis (AE) is a rare zoonosis caused by the larval stage of the tapeworm Echinococcus multilocularis. AE lesions affect the liver in more than 98% of cases. AE lesions have various morphological characteristics that are described in the Echinococcus multilocularis Ulm classification for computed tomography (EMUC-CT). One of these characteristics is a cystoid portion. The aim of the study was to compare the density of simple hepatic cysts with cystoid portions of AE lesions classified on the basis of the EMUC-CT. Hounsfield Unit (HU) measurements of the cystoid portions of all EMUC-CT type I-IV AE lesions (n = 155) gave a mean of 21.8 ± 17.6, which was significantly different from that of 2.9 ± 4.5 for the simple hepatic cysts (p < 0.0001). The difference between each of the individual AE types and simple hepatic cysts was also significant. In addition, the HU values of the cystoid portions in types I, II and IIIa/b and simple cysts were each significantly different from type IV (p < 0.0001). The HU measurements in type IV presented by far the highest mean. The significantly higher density measured in the cystoid portions of hepatic AE lesions offers a good means of differentiation from simple hepatic cysts.
Sections du résumé
BACKGROUND
BACKGROUND
Alveolar echinococcosis (AE) is a rare zoonosis caused by the larval stage of the tapeworm Echinococcus multilocularis. AE lesions affect the liver in more than 98% of cases. AE lesions have various morphological characteristics that are described in the Echinococcus multilocularis Ulm classification for computed tomography (EMUC-CT). One of these characteristics is a cystoid portion. The aim of the study was to compare the density of simple hepatic cysts with cystoid portions of AE lesions classified on the basis of the EMUC-CT.
RESULTS
RESULTS
Hounsfield Unit (HU) measurements of the cystoid portions of all EMUC-CT type I-IV AE lesions (n = 155) gave a mean of 21.8 ± 17.6, which was significantly different from that of 2.9 ± 4.5 for the simple hepatic cysts (p < 0.0001). The difference between each of the individual AE types and simple hepatic cysts was also significant. In addition, the HU values of the cystoid portions in types I, II and IIIa/b and simple cysts were each significantly different from type IV (p < 0.0001). The HU measurements in type IV presented by far the highest mean.
CONCLUSIONS
CONCLUSIONS
The significantly higher density measured in the cystoid portions of hepatic AE lesions offers a good means of differentiation from simple hepatic cysts.
Identifiants
pubmed: 31469072
doi: 10.1051/parasite/2019057
pii: parasite190064
pmc: PMC6716343
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
54Informations de copyright
© A. Engler et al., published by EDP Sciences, 2019.
Références
Acta Radiol. 2001 Mar;42(2):172-5
pubmed: 11259945
Infection. 2001 May-Jun;29(3):119-25
pubmed: 11440381
Emerg Infect Dis. 2003 Mar;9(3):343-9
pubmed: 12643830
Radiology. 2003 Jul;228(1):172-7
pubmed: 12750459
Clin Radiol. 2003 Aug;58(8):626-9
pubmed: 12887956
Clin Microbiol Rev. 2004 Jan;17(1):107-35
pubmed: 14726458
Hepatology. 2004 Feb;39(2):509-17
pubmed: 14768005
Parasitology. 2003;127 Suppl:S5-20
pubmed: 15027602
Br J Surg. 2005 Sep;92(9):1110-6
pubmed: 16044412
Clin Radiol. 2005 Sep;60(9):1026-9
pubmed: 16124985
Parasitol Int. 2006;55 Suppl:S283-7
pubmed: 16343985
Parasitol Int. 2006;55 Suppl:S267-72
pubmed: 16403670
Am J Trop Med Hyg. 2006 May;74(5):856-62
pubmed: 16687693
Langenbecks Arch Surg. 2009 Jul;394(4):689-98
pubmed: 18651165
Int J Infect Dis. 2009 Mar;13(2):125-33
pubmed: 18938096
Acta Trop. 2010 Apr;114(1):1-16
pubmed: 19931502
Radiographics. 2012 Nov-Dec;32(7):2053-70
pubmed: 23150858
World J Gastroenterol. 2013 Jun 21;19(23):3543-54
pubmed: 23801855
Radiographics. 2013 Sep-Oct;33(5):1419-33
pubmed: 24025933
Abdom Imaging. 2015 Jan;40(1):56-63
pubmed: 24970734
Turk J Gastroenterol. 2014 Aug;25(4):398-404
pubmed: 25254522
Radiologe. 2015 Jan;55(1):9-17
pubmed: 25575722
BMJ Case Rep. 2015 Feb 19;2015:null
pubmed: 25697300
Br J Radiol. 1989 Apr;62(736):335-7
pubmed: 2653548
Emerg Infect Dis. 2015 Dec;21(12):2263-5
pubmed: 26583699
World J Gastroenterol. 2015 Nov 21;21(43):12392-402
pubmed: 26604646
Abdom Radiol (NY). 2016 Jan;41(1):25-32
pubmed: 26830608
World J Gastroenterol. 2016 Apr 7;22(13):3621-31
pubmed: 27053854
Diagn Interv Imaging. 2018 Mar;99(3):169-177
pubmed: 29110943
Eurasian J Med. 2018 Feb;50(1):1-5
pubmed: 29531482
Radiology. 1985 Jan;154(1):179-86
pubmed: 3880602
Br J Radiol. 1973 Dec;46(552):1016-22
pubmed: 4757352
Ann Surg. 1974 Jun;179(6):922-5
pubmed: 4835513
Trans R Soc Trop Med Hyg. 1993 May-Jun;87(3):319-21
pubmed: 8236407
Gastroenterol Clin North Am. 1996 Sep;25(3):655-89
pubmed: 8863045