Tug of War in the Xenophagy World.

Adenosine Triphosphatases Bacteria Bacterial Proteins / physiology Host-Pathogen Interactions Humans Macroautophagy Salmonella typhimurium
ADP ribosylation ATG16-L1 ATG5 SopF xenophagy

Journal

Trends in cell biology
ISSN: 1879-3088
Titre abrégé: Trends Cell Biol
Pays: England
ID NLM: 9200566

Informations de publication

Date de publication:
10 2019
Historique:
received: 01 08 2019
accepted: 02 08 2019
pubmed: 1 9 2019
medline: 8 7 2020
entrez: 1 9 2019
Statut: ppublish

Résumé

Xenophagy, the process of eliminating intracellular pathogens through the autophagy machinery, is an important defense mechanism against infectious disease, yet the underlying molecular mechanisms remain incompletely understood. Recent work (Xu et al., Cell, 2019) used the discovery of an inhibitor of xenophagy, SopF, to identify a SopF-sensitive mechanism that allows mammalian cells to detect invading bacteria.

Identifiants

DOI: 10.1016/j.tcb.2019.08.001 PMID: 31471010
pubmed: 31471010
pii: S0962-8924(19)30137-0
doi: 10.1016/j.tcb.2019.08.001
pii:
doi:

Substances chimiques

Bacterial Proteins 0
Adenosine Triphosphatases EC 3.6.1.-

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

767-769

Informations de copyright

Copyright © 2019 Elsevier Ltd. All rights reserved.

Auteurs

Kuan Chuan Pao (KC)

Howard Hughes Medical Institute, University of California at Berkeley, Berkeley, CA 94720, USA; Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA 94720, USA.

Michael Rape (M)

Howard Hughes Medical Institute, University of California at Berkeley, Berkeley, CA 94720, USA; Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA 94720, USA. Electronic address: mrape@berkeley.edu.

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Classifications MeSH

questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Acid anhydride hydrolases › Adenosine triphosphatases › Tug of War in the Xenophagy World.
questionsmedicales.fr › Bactéries › Tug of War in the Xenophagy World.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines bactériennes › Tug of War in the Xenophagy World.
questionsmedicales.fr › Phénomènes biologiques › Interactions hôte-microbes › Interactions hôte-pathogène › Tug of War in the Xenophagy World.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Tug of War in the Xenophagy World.
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Autophagie › Macroautophagie › Tug of War in the Xenophagy World.
questionsmedicales.fr › Bactéries › Proteobacteria › Gammaproteobacteria › Enterobacteriaceae › Salmonella › Salmonella enterica › Salmonella typhimurium › Tug of War in the Xenophagy World.