[Epidemiological, pathological and prognostic characteristics of bladder cancer in elderly patients].

Spécificités épidémiologiques, pathologiques et pronostiques du cancer de la vessie chez les patients âgés.
Bladder cancer Cancer de la vessie Elderly Epidemiology Pathologie Pathology Personne âgé Prognosis Pronostic Épidémiologie

Journal

Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie
ISSN: 1166-7087
Titre abrégé: Prog Urol
Pays: France
ID NLM: 9307844

Informations de publication

Date de publication:
Nov 2019
Historique:
received: 31 07 2019
accepted: 08 08 2019
pubmed: 1 9 2019
medline: 10 4 2020
entrez: 1 9 2019
Statut: ppublish

Résumé

To define and present explanations for the epidemiological, pathological and prognostic differences in bladder cancer in elderly patients. Bibliographical search was performed from the Medline bibliographic database (NLM Pubmed tool) and Embase focused on: bladder cancer, carcinogenesis, elderly, epidemiology, prognosis. Bladder cancer is a growing concern for the elderly first and foremost and with an impact, mainly those who are consumers or former users of tobacco, whose therefore frequently have comorbidities associated with this consumption. The initiated carcinogenesis extends with the life length of patients, increasing the prevalence of bladder cancer. Aging promotes carcinogenesis by both potentiating its genetic abnormalities and reducing the immune system performance of the aged host to destroy cancer cells. The delay in the diagnosis of bladder cancer in elderly patients is explained and make up for the time could improve the prognosis. Regardless of variations in therapeutic effect and morbidity and mortality of treatments, aging promotes the occurrence and aggressiveness of bladder cancer. The incentive to stop exposure to carcinogens and the search for bladder cancer in patients with hematuria should not reduce with advanced age but instead be promoted in order to improve the prognosis.

Identifiants

pubmed: 31471266
pii: S1166-7087(19)30456-7
doi: 10.1016/j.purol.2019.08.268
pii:
doi:

Types de publication

Journal Article Review

Langues

fre

Sous-ensembles de citation

IM

Pagination

840-848

Informations de copyright

Copyright © 2019 Elsevier Masson SAS. All rights reserved.

Auteurs

Y Neuzillet (Y)

Service d'urologie et de transplantation rénale, hôpital Foch, université de Versailles - Saint-Quentin-en-Yvelines, 40, rue Worth, 92150 Suresnes, France. Electronic address: y.neuzillet@hopital-foch.org.

R Geiss (R)

Unité d'oncogériatrie, service de gériatrie, hôpital européen Georges-Pompidou, université de Paris Descartes, 20, rue Leblanc, 75908 Paris cedex 15, France.

P Caillet (P)

Unité d'oncogériatrie, service de gériatrie, hôpital européen Georges-Pompidou, université de Paris Descartes, 20, rue Leblanc, 75908 Paris cedex 15, France.

E Paillaud (E)

Unité d'oncogériatrie, service de gériatrie, hôpital européen Georges-Pompidou, université de Paris Descartes, 20, rue Leblanc, 75908 Paris cedex 15, France.

P Mongiat-Artus (P)

Unité de chirurgie et d'anesthésie ambulatoires, service d'urologie, Inserm UMR, S1165, hôpital Saint-Louis, université de Paris-7-Denis-Diderot, 1, avenue Claude-Vellefaux, 75010 Paris, France.

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Classifications MeSH