Intergenerational monitoring in clinical trials of germline gene editing.
Clinical trials
Gene Therapy/Transfer
Reproductive Medicine
Research Ethics
Journal
Journal of medical ethics
ISSN: 1473-4257
Titre abrégé: J Med Ethics
Pays: England
ID NLM: 7513619
Informations de publication
Date de publication:
03 2020
03 2020
Historique:
received:
12
06
2019
revised:
14
08
2019
accepted:
21
08
2019
pubmed:
2
9
2019
medline:
18
9
2021
entrez:
2
9
2019
Statut:
ppublish
Résumé
Design of clinical trials for germline gene editing stretches current accepted standards for human subjects research. Among the challenges involved is a set of issues concerning
Identifiants
pubmed: 31473657
pii: medethics-2019-105620
doi: 10.1136/medethics-2019-105620
pmc: PMC7036322
mid: NIHMS1050009
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
183-187Subventions
Organisme : NHGRI NIH HHS
ID : R03 HG010417
Pays : United States
Informations de copyright
© Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: BC reports grants from the National Human Genome Research Institute during the conduct of the study. Shoukhrat Mitalipov, director of the Oregon Health and Science University Center for Embryonic, Cell, and Gene Therapy, and principal investigator and coauthor of two studies on germline gene therapy cited in this paper, is on the advisory committee for a grant that funded work on this paper.
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