The Relationship Between Physical Examination and Ultrasonography of Large Entheses of the Achilles Tendon and Patellar Tendon Origin.


Journal

The Journal of rheumatology
ISSN: 0315-162X
Titre abrégé: J Rheumatol
Pays: Canada
ID NLM: 7501984

Informations de publication

Date de publication:
01 07 2020
Historique:
accepted: 22 08 2019
pubmed: 3 9 2019
medline: 1 9 2021
entrez: 3 9 2019
Statut: ppublish

Résumé

To investigate the relationship between physical examination (PE) and sonographic features of enthesitis, based on anatomical sites. The analysis was done using merged raw data of 3 studies on 2298 entheses. Patients with clinical Achilles enthesitis had more abnormalities on ultrasound (US): hypoechogenicity, p < 0.001; thickening, p = 0.001; Doppler signals, p = 0.002; and erosions, p = 0.02. The patellar tendon origin also correlated with PE but distal patellar tendon insertion and plantar aponeurosis were uncoupled from the US. The relationship between clinical and sonographic findings for large entheses is dependent on the anatomical site. For the patellar tendon origin and Achilles entheses, PE is significantly linked to US findings.

Identifiants

pubmed: 31474590
pii: jrheum.190169
doi: 10.3899/jrheum.190169
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1026-1030

Auteurs

Sibel Zehra Aydin (SZ)

From the University of Ottawa Faculty of Medicine, Ottawa Hospital Research Institute, Department of Internal Medicine, Division of Rheumatology, Ottawa, Ontario, Canada; Istanbul Medeniyet University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey; Complejo Hospitalario Torrecárdenas, Department of Internal Medicine, Division of Rheumatology, Almería, Spain; UK National Institute for Health Research (NIHR) Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; University of California, Department of Statistics, Riverside, California, USA; University of Toronto, Department of Internal Medicine, Division of Rheumatology, Krembil Research Institute, Toronto Western Hospital; University of Toronto, Women's College Research Institute, Women's College Hospital, Rheumatology, Toronto, Ontario, Canada. saydin@toh.ca.
S.Z. Aydin, MD, Assoc. Professor, University of Ottawa Faculty of Medicine, Ottawa Hospital Research Institute, Department of Internal Medicine, Division of Rheumatology; S. Bakirci, MD, University of Ottawa Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology; E. Kasapoglu, MD, Assoc. Professor, Istanbul Medeniyet University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology; C. Castillo-Gallego, MD, Complejo Hospitalario Torrecárdenas, Department of Internal Medicine, Division of Rheumatology; F. Arslan Alhussain, MD, Istanbul Medeniyet University, Department of Internal Medicine; Z.R. Ash, MD, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; E. Kurum, PhD, Assistant Professor, University of California, Department of Statistics; D. McGonagle, MD, Professor, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; H. Marzo-Ortega, MD, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; D. Gladman, MD, Professor of Medicine, University of Toronto, Department of Internal Medicine, Division of Rheumatology, Krembil Research Institute, Toronto Western Hospital; L. Eder, MD, PhD, Assistant Professor, University of Toronto, Women's College Research Institute, Women's College Hospital, Rheumatology. saydin@toh.ca.

Sibel Bakirci (S)

From the University of Ottawa Faculty of Medicine, Ottawa Hospital Research Institute, Department of Internal Medicine, Division of Rheumatology, Ottawa, Ontario, Canada; Istanbul Medeniyet University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey; Complejo Hospitalario Torrecárdenas, Department of Internal Medicine, Division of Rheumatology, Almería, Spain; UK National Institute for Health Research (NIHR) Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; University of California, Department of Statistics, Riverside, California, USA; University of Toronto, Department of Internal Medicine, Division of Rheumatology, Krembil Research Institute, Toronto Western Hospital; University of Toronto, Women's College Research Institute, Women's College Hospital, Rheumatology, Toronto, Ontario, Canada.
S.Z. Aydin, MD, Assoc. Professor, University of Ottawa Faculty of Medicine, Ottawa Hospital Research Institute, Department of Internal Medicine, Division of Rheumatology; S. Bakirci, MD, University of Ottawa Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology; E. Kasapoglu, MD, Assoc. Professor, Istanbul Medeniyet University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology; C. Castillo-Gallego, MD, Complejo Hospitalario Torrecárdenas, Department of Internal Medicine, Division of Rheumatology; F. Arslan Alhussain, MD, Istanbul Medeniyet University, Department of Internal Medicine; Z.R. Ash, MD, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; E. Kurum, PhD, Assistant Professor, University of California, Department of Statistics; D. McGonagle, MD, Professor, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; H. Marzo-Ortega, MD, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; D. Gladman, MD, Professor of Medicine, University of Toronto, Department of Internal Medicine, Division of Rheumatology, Krembil Research Institute, Toronto Western Hospital; L. Eder, MD, PhD, Assistant Professor, University of Toronto, Women's College Research Institute, Women's College Hospital, Rheumatology.

Esen Kasapoglu (E)

From the University of Ottawa Faculty of Medicine, Ottawa Hospital Research Institute, Department of Internal Medicine, Division of Rheumatology, Ottawa, Ontario, Canada; Istanbul Medeniyet University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey; Complejo Hospitalario Torrecárdenas, Department of Internal Medicine, Division of Rheumatology, Almería, Spain; UK National Institute for Health Research (NIHR) Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; University of California, Department of Statistics, Riverside, California, USA; University of Toronto, Department of Internal Medicine, Division of Rheumatology, Krembil Research Institute, Toronto Western Hospital; University of Toronto, Women's College Research Institute, Women's College Hospital, Rheumatology, Toronto, Ontario, Canada.
S.Z. Aydin, MD, Assoc. Professor, University of Ottawa Faculty of Medicine, Ottawa Hospital Research Institute, Department of Internal Medicine, Division of Rheumatology; S. Bakirci, MD, University of Ottawa Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology; E. Kasapoglu, MD, Assoc. Professor, Istanbul Medeniyet University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology; C. Castillo-Gallego, MD, Complejo Hospitalario Torrecárdenas, Department of Internal Medicine, Division of Rheumatology; F. Arslan Alhussain, MD, Istanbul Medeniyet University, Department of Internal Medicine; Z.R. Ash, MD, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; E. Kurum, PhD, Assistant Professor, University of California, Department of Statistics; D. McGonagle, MD, Professor, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; H. Marzo-Ortega, MD, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; D. Gladman, MD, Professor of Medicine, University of Toronto, Department of Internal Medicine, Division of Rheumatology, Krembil Research Institute, Toronto Western Hospital; L. Eder, MD, PhD, Assistant Professor, University of Toronto, Women's College Research Institute, Women's College Hospital, Rheumatology.

Concepcion Castillo-Gallego (C)

From the University of Ottawa Faculty of Medicine, Ottawa Hospital Research Institute, Department of Internal Medicine, Division of Rheumatology, Ottawa, Ontario, Canada; Istanbul Medeniyet University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey; Complejo Hospitalario Torrecárdenas, Department of Internal Medicine, Division of Rheumatology, Almería, Spain; UK National Institute for Health Research (NIHR) Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; University of California, Department of Statistics, Riverside, California, USA; University of Toronto, Department of Internal Medicine, Division of Rheumatology, Krembil Research Institute, Toronto Western Hospital; University of Toronto, Women's College Research Institute, Women's College Hospital, Rheumatology, Toronto, Ontario, Canada.
S.Z. Aydin, MD, Assoc. Professor, University of Ottawa Faculty of Medicine, Ottawa Hospital Research Institute, Department of Internal Medicine, Division of Rheumatology; S. Bakirci, MD, University of Ottawa Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology; E. Kasapoglu, MD, Assoc. Professor, Istanbul Medeniyet University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology; C. Castillo-Gallego, MD, Complejo Hospitalario Torrecárdenas, Department of Internal Medicine, Division of Rheumatology; F. Arslan Alhussain, MD, Istanbul Medeniyet University, Department of Internal Medicine; Z.R. Ash, MD, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; E. Kurum, PhD, Assistant Professor, University of California, Department of Statistics; D. McGonagle, MD, Professor, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; H. Marzo-Ortega, MD, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; D. Gladman, MD, Professor of Medicine, University of Toronto, Department of Internal Medicine, Division of Rheumatology, Krembil Research Institute, Toronto Western Hospital; L. Eder, MD, PhD, Assistant Professor, University of Toronto, Women's College Research Institute, Women's College Hospital, Rheumatology.

Fatıma Arslan Alhussain (FA)

From the University of Ottawa Faculty of Medicine, Ottawa Hospital Research Institute, Department of Internal Medicine, Division of Rheumatology, Ottawa, Ontario, Canada; Istanbul Medeniyet University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey; Complejo Hospitalario Torrecárdenas, Department of Internal Medicine, Division of Rheumatology, Almería, Spain; UK National Institute for Health Research (NIHR) Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; University of California, Department of Statistics, Riverside, California, USA; University of Toronto, Department of Internal Medicine, Division of Rheumatology, Krembil Research Institute, Toronto Western Hospital; University of Toronto, Women's College Research Institute, Women's College Hospital, Rheumatology, Toronto, Ontario, Canada.
S.Z. Aydin, MD, Assoc. Professor, University of Ottawa Faculty of Medicine, Ottawa Hospital Research Institute, Department of Internal Medicine, Division of Rheumatology; S. Bakirci, MD, University of Ottawa Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology; E. Kasapoglu, MD, Assoc. Professor, Istanbul Medeniyet University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology; C. Castillo-Gallego, MD, Complejo Hospitalario Torrecárdenas, Department of Internal Medicine, Division of Rheumatology; F. Arslan Alhussain, MD, Istanbul Medeniyet University, Department of Internal Medicine; Z.R. Ash, MD, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; E. Kurum, PhD, Assistant Professor, University of California, Department of Statistics; D. McGonagle, MD, Professor, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; H. Marzo-Ortega, MD, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; D. Gladman, MD, Professor of Medicine, University of Toronto, Department of Internal Medicine, Division of Rheumatology, Krembil Research Institute, Toronto Western Hospital; L. Eder, MD, PhD, Assistant Professor, University of Toronto, Women's College Research Institute, Women's College Hospital, Rheumatology.

Zoe R Ash (ZR)

From the University of Ottawa Faculty of Medicine, Ottawa Hospital Research Institute, Department of Internal Medicine, Division of Rheumatology, Ottawa, Ontario, Canada; Istanbul Medeniyet University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey; Complejo Hospitalario Torrecárdenas, Department of Internal Medicine, Division of Rheumatology, Almería, Spain; UK National Institute for Health Research (NIHR) Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; University of California, Department of Statistics, Riverside, California, USA; University of Toronto, Department of Internal Medicine, Division of Rheumatology, Krembil Research Institute, Toronto Western Hospital; University of Toronto, Women's College Research Institute, Women's College Hospital, Rheumatology, Toronto, Ontario, Canada.
S.Z. Aydin, MD, Assoc. Professor, University of Ottawa Faculty of Medicine, Ottawa Hospital Research Institute, Department of Internal Medicine, Division of Rheumatology; S. Bakirci, MD, University of Ottawa Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology; E. Kasapoglu, MD, Assoc. Professor, Istanbul Medeniyet University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology; C. Castillo-Gallego, MD, Complejo Hospitalario Torrecárdenas, Department of Internal Medicine, Division of Rheumatology; F. Arslan Alhussain, MD, Istanbul Medeniyet University, Department of Internal Medicine; Z.R. Ash, MD, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; E. Kurum, PhD, Assistant Professor, University of California, Department of Statistics; D. McGonagle, MD, Professor, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; H. Marzo-Ortega, MD, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; D. Gladman, MD, Professor of Medicine, University of Toronto, Department of Internal Medicine, Division of Rheumatology, Krembil Research Institute, Toronto Western Hospital; L. Eder, MD, PhD, Assistant Professor, University of Toronto, Women's College Research Institute, Women's College Hospital, Rheumatology.

Esra Kurum (E)

From the University of Ottawa Faculty of Medicine, Ottawa Hospital Research Institute, Department of Internal Medicine, Division of Rheumatology, Ottawa, Ontario, Canada; Istanbul Medeniyet University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey; Complejo Hospitalario Torrecárdenas, Department of Internal Medicine, Division of Rheumatology, Almería, Spain; UK National Institute for Health Research (NIHR) Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; University of California, Department of Statistics, Riverside, California, USA; University of Toronto, Department of Internal Medicine, Division of Rheumatology, Krembil Research Institute, Toronto Western Hospital; University of Toronto, Women's College Research Institute, Women's College Hospital, Rheumatology, Toronto, Ontario, Canada.
S.Z. Aydin, MD, Assoc. Professor, University of Ottawa Faculty of Medicine, Ottawa Hospital Research Institute, Department of Internal Medicine, Division of Rheumatology; S. Bakirci, MD, University of Ottawa Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology; E. Kasapoglu, MD, Assoc. Professor, Istanbul Medeniyet University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology; C. Castillo-Gallego, MD, Complejo Hospitalario Torrecárdenas, Department of Internal Medicine, Division of Rheumatology; F. Arslan Alhussain, MD, Istanbul Medeniyet University, Department of Internal Medicine; Z.R. Ash, MD, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; E. Kurum, PhD, Assistant Professor, University of California, Department of Statistics; D. McGonagle, MD, Professor, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; H. Marzo-Ortega, MD, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; D. Gladman, MD, Professor of Medicine, University of Toronto, Department of Internal Medicine, Division of Rheumatology, Krembil Research Institute, Toronto Western Hospital; L. Eder, MD, PhD, Assistant Professor, University of Toronto, Women's College Research Institute, Women's College Hospital, Rheumatology.

Dennis McGonagle (D)

From the University of Ottawa Faculty of Medicine, Ottawa Hospital Research Institute, Department of Internal Medicine, Division of Rheumatology, Ottawa, Ontario, Canada; Istanbul Medeniyet University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey; Complejo Hospitalario Torrecárdenas, Department of Internal Medicine, Division of Rheumatology, Almería, Spain; UK National Institute for Health Research (NIHR) Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; University of California, Department of Statistics, Riverside, California, USA; University of Toronto, Department of Internal Medicine, Division of Rheumatology, Krembil Research Institute, Toronto Western Hospital; University of Toronto, Women's College Research Institute, Women's College Hospital, Rheumatology, Toronto, Ontario, Canada.
S.Z. Aydin, MD, Assoc. Professor, University of Ottawa Faculty of Medicine, Ottawa Hospital Research Institute, Department of Internal Medicine, Division of Rheumatology; S. Bakirci, MD, University of Ottawa Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology; E. Kasapoglu, MD, Assoc. Professor, Istanbul Medeniyet University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology; C. Castillo-Gallego, MD, Complejo Hospitalario Torrecárdenas, Department of Internal Medicine, Division of Rheumatology; F. Arslan Alhussain, MD, Istanbul Medeniyet University, Department of Internal Medicine; Z.R. Ash, MD, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; E. Kurum, PhD, Assistant Professor, University of California, Department of Statistics; D. McGonagle, MD, Professor, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; H. Marzo-Ortega, MD, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; D. Gladman, MD, Professor of Medicine, University of Toronto, Department of Internal Medicine, Division of Rheumatology, Krembil Research Institute, Toronto Western Hospital; L. Eder, MD, PhD, Assistant Professor, University of Toronto, Women's College Research Institute, Women's College Hospital, Rheumatology.

Helena Marzo-Ortega (H)

From the University of Ottawa Faculty of Medicine, Ottawa Hospital Research Institute, Department of Internal Medicine, Division of Rheumatology, Ottawa, Ontario, Canada; Istanbul Medeniyet University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey; Complejo Hospitalario Torrecárdenas, Department of Internal Medicine, Division of Rheumatology, Almería, Spain; UK National Institute for Health Research (NIHR) Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; University of California, Department of Statistics, Riverside, California, USA; University of Toronto, Department of Internal Medicine, Division of Rheumatology, Krembil Research Institute, Toronto Western Hospital; University of Toronto, Women's College Research Institute, Women's College Hospital, Rheumatology, Toronto, Ontario, Canada.
S.Z. Aydin, MD, Assoc. Professor, University of Ottawa Faculty of Medicine, Ottawa Hospital Research Institute, Department of Internal Medicine, Division of Rheumatology; S. Bakirci, MD, University of Ottawa Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology; E. Kasapoglu, MD, Assoc. Professor, Istanbul Medeniyet University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology; C. Castillo-Gallego, MD, Complejo Hospitalario Torrecárdenas, Department of Internal Medicine, Division of Rheumatology; F. Arslan Alhussain, MD, Istanbul Medeniyet University, Department of Internal Medicine; Z.R. Ash, MD, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; E. Kurum, PhD, Assistant Professor, University of California, Department of Statistics; D. McGonagle, MD, Professor, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; H. Marzo-Ortega, MD, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; D. Gladman, MD, Professor of Medicine, University of Toronto, Department of Internal Medicine, Division of Rheumatology, Krembil Research Institute, Toronto Western Hospital; L. Eder, MD, PhD, Assistant Professor, University of Toronto, Women's College Research Institute, Women's College Hospital, Rheumatology.

Dafna Gladman (D)

From the University of Ottawa Faculty of Medicine, Ottawa Hospital Research Institute, Department of Internal Medicine, Division of Rheumatology, Ottawa, Ontario, Canada; Istanbul Medeniyet University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey; Complejo Hospitalario Torrecárdenas, Department of Internal Medicine, Division of Rheumatology, Almería, Spain; UK National Institute for Health Research (NIHR) Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; University of California, Department of Statistics, Riverside, California, USA; University of Toronto, Department of Internal Medicine, Division of Rheumatology, Krembil Research Institute, Toronto Western Hospital; University of Toronto, Women's College Research Institute, Women's College Hospital, Rheumatology, Toronto, Ontario, Canada.
S.Z. Aydin, MD, Assoc. Professor, University of Ottawa Faculty of Medicine, Ottawa Hospital Research Institute, Department of Internal Medicine, Division of Rheumatology; S. Bakirci, MD, University of Ottawa Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology; E. Kasapoglu, MD, Assoc. Professor, Istanbul Medeniyet University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology; C. Castillo-Gallego, MD, Complejo Hospitalario Torrecárdenas, Department of Internal Medicine, Division of Rheumatology; F. Arslan Alhussain, MD, Istanbul Medeniyet University, Department of Internal Medicine; Z.R. Ash, MD, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; E. Kurum, PhD, Assistant Professor, University of California, Department of Statistics; D. McGonagle, MD, Professor, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; H. Marzo-Ortega, MD, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; D. Gladman, MD, Professor of Medicine, University of Toronto, Department of Internal Medicine, Division of Rheumatology, Krembil Research Institute, Toronto Western Hospital; L. Eder, MD, PhD, Assistant Professor, University of Toronto, Women's College Research Institute, Women's College Hospital, Rheumatology.

Lihi Eder (L)

From the University of Ottawa Faculty of Medicine, Ottawa Hospital Research Institute, Department of Internal Medicine, Division of Rheumatology, Ottawa, Ontario, Canada; Istanbul Medeniyet University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey; Complejo Hospitalario Torrecárdenas, Department of Internal Medicine, Division of Rheumatology, Almería, Spain; UK National Institute for Health Research (NIHR) Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; University of California, Department of Statistics, Riverside, California, USA; University of Toronto, Department of Internal Medicine, Division of Rheumatology, Krembil Research Institute, Toronto Western Hospital; University of Toronto, Women's College Research Institute, Women's College Hospital, Rheumatology, Toronto, Ontario, Canada.
S.Z. Aydin, MD, Assoc. Professor, University of Ottawa Faculty of Medicine, Ottawa Hospital Research Institute, Department of Internal Medicine, Division of Rheumatology; S. Bakirci, MD, University of Ottawa Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology; E. Kasapoglu, MD, Assoc. Professor, Istanbul Medeniyet University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology; C. Castillo-Gallego, MD, Complejo Hospitalario Torrecárdenas, Department of Internal Medicine, Division of Rheumatology; F. Arslan Alhussain, MD, Istanbul Medeniyet University, Department of Internal Medicine; Z.R. Ash, MD, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; E. Kurum, PhD, Assistant Professor, University of California, Department of Statistics; D. McGonagle, MD, Professor, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; H. Marzo-Ortega, MD, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; D. Gladman, MD, Professor of Medicine, University of Toronto, Department of Internal Medicine, Division of Rheumatology, Krembil Research Institute, Toronto Western Hospital; L. Eder, MD, PhD, Assistant Professor, University of Toronto, Women's College Research Institute, Women's College Hospital, Rheumatology.

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