Clinical utility of fecal calprotectin: potential applications beyond inflammatory bowel disease for the primary care physician.
Fecal calprotectin
non-inflammatory bowel disease
potential clinical application
Journal
Annals of gastroenterology
ISSN: 1108-7471
Titre abrégé: Ann Gastroenterol
Pays: Greece
ID NLM: 101121847
Informations de publication
Date de publication:
Historique:
received:
18
01
2019
accepted:
01
04
2019
entrez:
3
9
2019
pubmed:
3
9
2019
medline:
3
9
2019
Statut:
ppublish
Résumé
Fecal calprotectin (FC) is an inflammatory marker released mainly from gastrointestinal granulocytes measured in stool samples. FC is noninvasive, economical, simple, and acceptable for patients. Levels of FC have proven reliable for intestinal inflammation, with good clinical sensitivity, and are useful in screening and monitoring inflammatory bowel disease (IBD), as well as in the differential diagnosis between IBD and irritable bowel syndrome (IBS). Given its advantages, FC represents an attractive biomarker that could be utilized in various gastrointestinal (GI) diseases apart from IBD, and is currently being studied extensively by many research groups with significant amounts of data emerging. In this current review we aim to provide an outline of the utility of FC in distinguishing between IBS and IBD, as well as an up-to-date summary of the available clinical experience concerning FC in various common conditions of the GI tract commonly encountered by gastroenterology practitioners, such as IBS, microscopic colitis, acute gastroenteritis,
Identifiants
pubmed: 31474787
doi: 10.20524/aog.2019.0394
pii: AnnGastroenterol-32-425
pmc: PMC6686087
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
425-430Déclaration de conflit d'intérêts
Conflict of Interest: None
Références
Scand J Gastroenterol. 1999 Jan;34(1):50-4
pubmed: 10048733
Pediatr Res. 2000 Mar;47(3):344-50
pubmed: 10709733
Gut. 2001 Sep;49(3):402-8
pubmed: 11511563
J Pediatr Gastroenterol Nutr. 2002 Mar;34(3):323-4; author reply 324-5
pubmed: 11964964
Gastroenterology. 2002 Aug;123(2):450-60
pubmed: 12145798
Scand J Gastroenterol. 1992 Sep;27(9):793-8
pubmed: 1411288
Dig Liver Dis. 2004 Jul;36(7):467-70
pubmed: 15285526
Gut. 2004 Sep;53(9):1329-33
pubmed: 15306594
Int J Radiat Oncol Biol Phys. 2006 Apr 1;64(5):1432-41
pubmed: 16580497
Inflamm Bowel Dis. 2006 Jun;12(6):524-34
pubmed: 16775498
Am J Gastroenterol. 2007 Apr;102(4):803-13
pubmed: 17324124
Eur J Gastroenterol Hepatol. 2007 Jul;19(7):567-74
pubmed: 17556903
Clin Infect Dis. 2007 Aug 1;45(3):302-7
pubmed: 17599306
Scand J Gastroenterol. 2007 Aug;42(8):957-61
pubmed: 17613925
J Gastroenterol. 2007 Sep;42(9):754-60
pubmed: 17876545
Int J Colorectal Dis. 2009 Jan;24(1):49-55
pubmed: 18941760
Am J Med. 2008 Dec;121(12):1099-106
pubmed: 19028207
Am J Gastroenterol. 2009 Feb;104(2):404-10
pubmed: 19174795
Dig Liver Dis. 2010 Mar;42(3):191-5
pubmed: 19695969
J Clin Gastroenterol. 2010 Sep;44(8):544-6
pubmed: 20054281
Acta Paediatr. 2010 Sep;99(9):1389-95
pubmed: 20412103
Gastroenterol Clin North Am. 2011 Mar;40(1):105-19
pubmed: 21333903
Liver Int. 2011 Oct;31(9):1406-15
pubmed: 22093455
Blood. 2012 Jun 14;119(24):5909-17
pubmed: 22555971
Dig Dis. 2012;30(1):12-8
pubmed: 22572679
J Pediatr Gastroenterol Nutr. 2012 Nov;55(5):541-7
pubmed: 22699836
Turk J Gastroenterol. 2012;23(5):503-8
pubmed: 23161294
Blood. 2012 Nov 22;120(22):4443-4
pubmed: 23175663
Clin Chim Acta. 2013 Feb 1;416:41-7
pubmed: 23178549
Health Technol Assess. 2013 Nov;17(55):xv-xix, 1-211
pubmed: 24286461
World J Gastroenterol. 2014 Jan 14;20(2):611-2
pubmed: 24574734
Gut. 2016 Jan;65(1):91-9
pubmed: 25765462
Nat Chem Biol. 2015 Oct;11(10):765-71
pubmed: 26302479
Clujul Med. 2014;87(3):163-5
pubmed: 26528017
Clin Exp Gastroenterol. 2016 Apr 21;9:97-103
pubmed: 27147826
Obes Surg. 2016 Dec;26(12):2974-2980
pubmed: 27216731
BMC Infect Dis. 2016 Jun 22;16:309
pubmed: 27334992
Mediators Inflamm. 2016;2016:2492081
pubmed: 27413251
Ann Lab Med. 2017 Jan;37(1):53-57
pubmed: 27834066
United European Gastroenterol J. 2017 Mar;5(2):261-269
pubmed: 28344794
Scand J Gastroenterol. 1993 Dec;28(12):1073-6
pubmed: 8303210
Mol Pathol. 1997 Jun;50(3):113-23
pubmed: 9292145