Different Gut Microbial Profiles in Sub-Saharan African and South Asian Women of Childbearing Age Are Primarily Associated With Dietary Intakes.
Democratic Republic of the Congo
India
Women
diet
microbiota
Journal
Frontiers in microbiology
ISSN: 1664-302X
Titre abrégé: Front Microbiol
Pays: Switzerland
ID NLM: 101548977
Informations de publication
Date de publication:
2019
2019
Historique:
received:
23
04
2019
accepted:
26
07
2019
entrez:
3
9
2019
pubmed:
3
9
2019
medline:
3
9
2019
Statut:
epublish
Résumé
To compare and characterize the gut microbiota in women of childbearing age from sub-Saharan Africa (the Democratic Republic of the Congo, DRC) and South Asia (India), in relation to dietary intakes. Women of childbearing age were recruited from rural DRC and India as part of the Women First (WF) preconception maternal nutrition trial. Findings presented include fecal 16S rRNA gene-based profiling of women in the WF trial from samples obtained at the time of randomization, prior to initiation of nutrition intervention and to conception. Stool samples were collected from 217 women (DRC Consumption of animal-flesh foods and fermented dairy foods were independently associated with the gut microbiota while demographic variables were not, suggesting that diet may have a stronger association with microbiota than demographic characteristics.
Sections du résumé
BACKGROUND
BACKGROUND
To compare and characterize the gut microbiota in women of childbearing age from sub-Saharan Africa (the Democratic Republic of the Congo, DRC) and South Asia (India), in relation to dietary intakes.
METHODS
METHODS
Women of childbearing age were recruited from rural DRC and India as part of the Women First (WF) preconception maternal nutrition trial. Findings presented include fecal 16S rRNA gene-based profiling of women in the WF trial from samples obtained at the time of randomization, prior to initiation of nutrition intervention and to conception.
RESULTS
RESULTS
Stool samples were collected from 217 women (DRC
CONCLUSION
CONCLUSIONS
Consumption of animal-flesh foods and fermented dairy foods were independently associated with the gut microbiota while demographic variables were not, suggesting that diet may have a stronger association with microbiota than demographic characteristics.
Identifiants
pubmed: 31474951
doi: 10.3389/fmicb.2019.01848
pmc: PMC6702451
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1848Subventions
Organisme : NICHD NIH HHS
ID : U10 HD076474
Pays : United States
Organisme : NICHD NIH HHS
ID : UG1 HD076474
Pays : United States
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