Human papillomavirus (HPV) vaccine and autonomic disorders: a position statement from the American Autonomic Society.
Autonomic Nervous System Diseases
/ chemically induced
Fatigue Syndrome, Chronic
/ chemically induced
Humans
Papillomavirus Infections
/ epidemiology
Papillomavirus Vaccines
/ administration & dosage
Postural Orthostatic Tachycardia Syndrome
/ chemically induced
Primary Dysautonomias
/ chemically induced
Societies, Medical
/ trends
United States
/ epidemiology
Autonomic dysfunction
Consensus statement
HPV
Postural tachycardia syndrome
Vaccine
Journal
Clinical autonomic research : official journal of the Clinical Autonomic Research Society
ISSN: 1619-1560
Titre abrégé: Clin Auton Res
Pays: Germany
ID NLM: 9106549
Informations de publication
Date de publication:
02 2020
02 2020
Historique:
received:
08
03
2019
accepted:
15
04
2019
pubmed:
3
9
2019
medline:
7
7
2021
entrez:
3
9
2019
Statut:
ppublish
Résumé
Human papillomavirus (HPV) vaccination has been anecdotally connected to the development of dysautonomia, chronic fatigue, complex regional pain syndrome and postural tachycardia syndrome. To critically evaluate a potential connection between HPV vaccination and the above-noted conditions. We reviewed the literature containing the biology of the virus, pathophysiology of infection, epidemiology of associated cancers, indications of HPV vaccination, safety surveillance data and published reports linking HPV vaccination to autonomic disorders. At this time, the American Autonomic Society finds that there are no data to support a causal relationship between HPV vaccination and CRPS, chronic fatigue, and postural tachycardia syndrome to other forms of dysautonomia. Certain conditions are prevalent in the same populations that are vaccinated with the HPV vaccine (peri-pubertal males and females). This association, however, is an insufficient proof of causality.
Identifiants
pubmed: 31475305
doi: 10.1007/s10286-019-00608-w
pii: 10.1007/s10286-019-00608-w
doi:
Substances chimiques
Papillomavirus Vaccines
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
13-18Subventions
Organisme : NIDDK NIH HHS
ID : R01 DK083538
Pays : United States
Commentaires et corrections
Type : CommentIn
Type : CommentIn
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