Evaluation of Aerosol Electrospray Analysis of Metal-on-Metal Wear Particles from Simulated Total Joint Replacement.
debris
implants
particles
prosthesis
wear
Journal
Sensors (Basel, Switzerland)
ISSN: 1424-8220
Titre abrégé: Sensors (Basel)
Pays: Switzerland
ID NLM: 101204366
Informations de publication
Date de publication:
30 Aug 2019
30 Aug 2019
Historique:
received:
12
07
2019
revised:
19
08
2019
accepted:
26
08
2019
entrez:
5
9
2019
pubmed:
5
9
2019
medline:
13
2
2020
Statut:
epublish
Résumé
Wear is a common cause for aseptic loosening in artificial joints. The purpose of this study was to develop an automated diagnostical method for identification of the number and size distribution of wear debris. For this purpose, metal debris samples were extracted from a hip simulator and then analyzed by the electrospray method combined with a differential mobility analyzer, allowing particle detection ranging from several nanometers up to 1 µm. Wear particles were identified with a characteristic peak at 15 nm. The electrospray setup was successfully used and validated for the first time to characterize wear debris from simulated total joint replacement. The advantages of this diagnostic method are its time- and financial efficiency and its suitability for testing of different materials.
Identifiants
pubmed: 31480227
pii: s19173751
doi: 10.3390/s19173751
pmc: PMC6749481
pii:
doi:
Substances chimiques
Aerosols
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Oesterreichische Nationalbank
ID : 13515
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