Myocardial ischemia in female patients with rheumatoid arthritis assessed with single photon emission tomography-myocardial perfusion imaging.
females
myocardial ischemia
myocardial perfusion imaging
rheumatoid arthritis
risk factors
tetrofosmin
Journal
Nuclear medicine review. Central & Eastern Europe
ISSN: 1644-4345
Titre abrégé: Nucl Med Rev Cent East Eur
Pays: Poland
ID NLM: 100886103
Informations de publication
Date de publication:
2019
2019
Historique:
received:
23
09
2018
accepted:
18
01
2019
revised:
14
01
2019
entrez:
5
9
2019
pubmed:
5
9
2019
medline:
25
4
2020
Statut:
ppublish
Résumé
Non-specific cardiac symptoms in female patients with rheumatoid arthritis (RA) could indicate early cardiovascular disease. Myocardial perfusion imaging (MPI), with 99mTc tetrofosmin stress-rest single photon emission computer tomography (SPECT), in 13 RA female patients with atypical cardiac symptoms, was compared to 44 weight- and age-matched females with similar cardiac complaints (control group). Smoking, hypertension, diabetes mellitus, dyslipidemia, obesity and cardiac heredity were recorded and compared between the study and control group. MPI was assessed using 17 segment polar map and with a scale of 0 to 5 scoring. Patients with RA demonstrated higher cardiovascular risk (46%) compared to control individuals (17%). In addition, patients with RA had more irreversible myocardial ischemic abnormalities in their MPI than the control group. Dyslipidemia and obesity was found more frequent in RA patients with MPI SSS ≥ 4. RA patients with atypical cardiac complaints are at higher risk for cardiovascular disease; early detection and monitoring of this patient group could potentially reverse or successfully manage the consequences of the upcoming cardiovascular disease.
Sections du résumé
BACKGROUND
BACKGROUND
Non-specific cardiac symptoms in female patients with rheumatoid arthritis (RA) could indicate early cardiovascular disease.
MATERIALS AND METHODS
METHODS
Myocardial perfusion imaging (MPI), with 99mTc tetrofosmin stress-rest single photon emission computer tomography (SPECT), in 13 RA female patients with atypical cardiac symptoms, was compared to 44 weight- and age-matched females with similar cardiac complaints (control group). Smoking, hypertension, diabetes mellitus, dyslipidemia, obesity and cardiac heredity were recorded and compared between the study and control group. MPI was assessed using 17 segment polar map and with a scale of 0 to 5 scoring.
RESULTS
RESULTS
Patients with RA demonstrated higher cardiovascular risk (46%) compared to control individuals (17%). In addition, patients with RA had more irreversible myocardial ischemic abnormalities in their MPI than the control group. Dyslipidemia and obesity was found more frequent in RA patients with MPI SSS ≥ 4.
CONCLUSION
CONCLUSIONS
RA patients with atypical cardiac complaints are at higher risk for cardiovascular disease; early detection and monitoring of this patient group could potentially reverse or successfully manage the consequences of the upcoming cardiovascular disease.
Identifiants
pubmed: 31482536
pii: VM/OJS/J/60147
doi: 10.5603/NMR.2019.0001
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM