Preoperative Factors Predicting Admission to the Intensive Care Unit After Kidney Transplantation.

ASA, American Society of Anesthesiologists BMI, body mass index CHF, congestive heart failure COPD, chronic obstructive pulmonary disease DM, diabetes mellitus ESRD, end-stage renal disease ICU, intensive care unit ILD, interstitial lung disease IQR, interquartile range MI, myocardial ischemia OR, odds ratio PVD, peripheral vascular disease WIT, warm ischemia time

Journal

Mayo Clinic proceedings. Innovations, quality & outcomes
ISSN: 2542-4548
Titre abrégé: Mayo Clin Proc Innov Qual Outcomes
Pays: Netherlands
ID NLM: 101728275

Informations de publication

Date de publication:
Sep 2019
Historique:
received: 23 05 2019
revised: 30 05 2019
accepted: 26 06 2019
entrez: 6 9 2019
pubmed: 6 9 2019
medline: 6 9 2019
Statut: epublish

Résumé

To identify preoperative factors predicting early admission (within 30 days) of adult kidney transplant recipients to the intensive care unit (ICU). This is a single-center retrospective study of consecutive kidney transplant recipients between January 1, 2007, and December 31, 2016. Children (aged <18 years) and patients who underwent simultaneous multiorgan transplantation were excluded from the analysis. Associations between demographic, transplant-related, and comorbidity variables with ICU admission within 30 days of transplantation were analyzed using univariate and multivariate logistic regression models. Of the 1527 eligible patients, 305 (20%) required early ICU admission. In univariate analysis, older age, higher body mass index (BMI), previous transplantation, myocardial infarction, congestive heart failure, obstructive pulmonary disease, longer ischemia time, pretransplant dialysis, and transplantation from a deceased donor were associated with increased odds of ICU admission. After multivariate adjustment, every 10-year increase in recipient age (odds ratio [OR], 1.26; 95% CI, 1.12-1.42; Recipient age, BMI, and the need for pretransplant dialysis are associated with a higher risk of early ICU admission after kidney transplantation, whereas living donor kidney transplantation and preemptive transplantation decrease these odds. Early referral of patients with end-stage renal disease for preemptive transplantation and living donor kidney transplantation can significantly reduce transplant-related ICU admissions.

Identifiants

pubmed: 31485566
doi: 10.1016/j.mayocpiqo.2019.06.008
pii: S2542-4548(19)30081-5
pmc: PMC6713836
doi:

Types de publication

Journal Article

Langues

eng

Pagination

285-293

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Auteurs

Nitin Abrol (N)

William J. von Liebig Center for Transplantation and Clinical Regeneration, Mayo Clinic, Rochester, MN.

Rahul Kashyap (R)

Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN.

Ryan D Frank (RD)

Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN.

Vivek N Iyer (VN)

Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN.

Patrick G Dean (PG)

William J. von Liebig Center for Transplantation and Clinical Regeneration, Mayo Clinic, Rochester, MN.

Mark D Stegall (MD)

William J. von Liebig Center for Transplantation and Clinical Regeneration, Mayo Clinic, Rochester, MN.

Mikel Prieto (M)

William J. von Liebig Center for Transplantation and Clinical Regeneration, Mayo Clinic, Rochester, MN.

Kianoush B Kashani (KB)

Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN.
Department Nephrology and Hypertension, Mayo Clinic, Rochester, MN.

Timucin Taner (T)

William J. von Liebig Center for Transplantation and Clinical Regeneration, Mayo Clinic, Rochester, MN.

Classifications MeSH