Effect of Weight Change Following Intentional Weight Loss on Bone Health in Older Adults with Obesity.
Journal
Obesity (Silver Spring, Md.)
ISSN: 1930-739X
Titre abrégé: Obesity (Silver Spring)
Pays: United States
ID NLM: 101264860
Informations de publication
Date de publication:
11 2019
11 2019
Historique:
received:
18
04
2019
accepted:
24
06
2019
pubmed:
6
9
2019
medline:
25
4
2020
entrez:
6
9
2019
Statut:
ppublish
Résumé
This study aimed to examine change in bone mineral density (BMD) and trabecular bone score among older adult weight regainers (WR) and weight maintainers (WM). Observational data come from 77 older adults (mean age: 67 [SD 5] years; 69% women; 70% white) with obesity (mean BMI: 33.6 [SD 3.7] kg/m Among skeletal indices, only total hip BMD was significantly reduced during the 18-month intervention period in both WRs (-3.9%; 95% CI: -5.8% to -2.0%) and WMs (-2.4%; 95% CI: -4.3% to -0.5%; P = 0.07). After adjustment for relevant baseline covariates and weight change from 0 to 18 months, 30-month change in total hip BMD was -2.6% (95% CI: -4.3% to -0.9%) and -3.9% (95% CI: -5.7% to -2.1%) among WRs and WMs, respectively (P = 0.07). Loss of hip BMD persists in the year after a weight loss intervention among older adults with obesity, regardless of weight regain status.
Identifiants
pubmed: 31486297
doi: 10.1002/oby.22604
pmc: PMC6832808
mid: NIHMS1534099
doi:
Banques de données
ClinicalTrials.gov
['NCT01547182']
Types de publication
Journal Article
Multicenter Study
Observational Study
Randomized Controlled Trial
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
1839-1845Subventions
Organisme : NIA NIH HHS
ID : K01 AG047921
Pays : United States
Organisme : NIA NIH HHS
ID : P30 AG021332
Pays : United States
Organisme : NHLBI NIH HHS
ID : R18 HL076441
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001420
Pays : United States
Informations de copyright
© 2019 The Obesity Society.
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