In vitro antimicrobial activity of a new ophthalmic solution containing povidone-iodine 0.6% (IODIM
Anti-Infective Agents, Local
/ pharmacology
Candida
/ drug effects
Colony Count, Microbial
Corneal Ulcer
/ microbiology
Culture Media
Humans
Microbial Sensitivity Tests
Ophthalmic Solutions
/ pharmacology
Pharmaceutical Preparations
Povidone-Iodine
/ pharmacology
Pseudomonas aeruginosa
/ drug effects
Staphylococcus aureus
/ drug effects
Staphylococcus epidermidis
/ drug effects
Time Factors
Pseudomonas aeruginosa
Staphylococcus aureus
Staphylococcus epidermidis
Candida species
in vitro antimicrobial activity
povidone-iodine 0.6%
Journal
Acta ophthalmologica
ISSN: 1755-3768
Titre abrégé: Acta Ophthalmol
Pays: England
ID NLM: 101468102
Informations de publication
Date de publication:
Mar 2020
Mar 2020
Historique:
received:
06
07
2019
accepted:
17
08
2019
pubmed:
6
9
2019
medline:
23
1
2021
entrez:
6
9
2019
Statut:
ppublish
Résumé
To assess the in vitro antimicrobial activity of a new commercial ophthalmic solution containing povidone-iodine 0.6% (IODIM Staphylococcus aureus ATCC 43300, Pseudomonas aeruginosa ATCC 27853, three ocular bacterial isolates (1 S. epidermidis, 1 S. aureus, 1 P. aeruginosa) and five Candida species were used. The bacterial and fungal isolates were cultured on Columbia blood agar base plates and Sabouraud-dextrose agar plates, respectively and incubated overnight at 37°C. Bacterial and fungal suspensions in sterile saline solution were prepared to an optical density equal to 0.5 McFarland standard (approximately 10 After 5-min incubation, there was no bacterial growth on any plate. Conversely, IODIM IODIM
Substances chimiques
Anti-Infective Agents, Local
0
Culture Media
0
Ophthalmic Solutions
0
Pharmaceutical Preparations
0
Povidone-Iodine
85H0HZU99M
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e178-e180Informations de copyright
© 2019 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.
Références
Alexandrakis G, Alfonso EC & Miller D (2000): Shifting trends in bacterial keratitis in south Florida and emerging resistance to fluoroquinolones. Ophthalmology 107: 1497-1502.
American Academy of Ophthalmology (2018): Bacterial keratitis Preferred Practice Patterns. Available at: https://www.aao.org/preferred-practice-pattern/bacterial-keratitis-ppp-2018 (Accessed on 13 Aug 2019).
Burks RI (1998): Povidone-iodine solution in wound treatment. Phys Ther 78: 212-218.
Ciulla TA, Starr MB & Masket S (2002): Bacterial endophthalmitis prophylaxis for cataract surgery: an evidence-based update. Ophthalmology 109: 13-26.
Costerton JW, Lewandowski Z, DeBeer D, Caldwell D, Korber D & James G (1994): Biofilms, the customized micronish. J Bacteriol 176: 2137-2142.
Gottardi W (1991): Iodine and iodine compounds. In: Seymour & SB (ed.) Disinfection, sterilization, and preservation. 4th ed. Philadelphia: Lea & Febiger 152-181.
Hwang DG (2004): Fluoroquinolone resistance in ophthalmology and the potential role for newer ophthalmic fluoroquinolones. Surv Ophthalmol 49:(suppl 49(suppl 2): S79-S83.
Imamura Y, Chandra J, Mukherjee PK et al. (2008): Fusarium and Candida albicans biofilms on soft contact lenses: model development, influence of lens type, and susceptibility to lens care solutions. Antimicrob Agents Chemother 52: 171-182.
Isenberg SJ, Apt L, Valenton M et al. (2017): Prospective, randomized clinical trial of povidone-iodine 1.25% solution versus topical antibiotics for treatment of bacterial keratitis. Am J Ophthalmol 176: 244-253.
Kim SJ & Toma HS (2011): Antimicrobial resistance and ophthalmic antibiotics: 1-year results of a longitudinal controlled study of patients undergoing intravitreal injections. Arch Ophthalmol 129: 1180-1188.
Kondo S, Tabe Y, Yamada T, Misawa S, Oguri T, Ohsaka A & Miida T (2012): Comparison of antifungal activities of gentian violet and povidone-iodine against clinical isolates of Candida species and other yeasts: a framework to establish topical disinfectant activities. Mycopathologia 173: 21-25.
Kreslov MS, Castellarin AA & Zarbin MA (1998): Endophthalmitis. Surv Ophthalmol 43: 193-224.
Leaming DV, American Society of Cataract and Refractive Surgery (2001): Practice styles and preferences of ASCRS members: 2000 survey. J Cataract Refract Surg 27: 948-955.
Miller JJ, Scott IU, Flynn HW Jr, Smiddy WE, Newton J & Miller D (2005): Acute-onset endophthalmitis after cataract surgery (2000-2004): incidence, clinical settings, and visual acuity outcomes after treatment. Am J Ophthalmol 139: 983-987.
Moss JM, Sanislo SR & Ta CN (2009): A prospective randomized evaluation of topical gatifloxacin on conjunctival flora in patients undergoing intravitreal injections. Ophthalmology 116: 1498-1501.
Musumeci R, Bandello F, Martinelli M, Calaresu E & Cocuzza CE (2018): In vitro bactericidal activity of 0.6% povidone-iodine eye drops formulation. Eur J Ophthalmol 2018: 1120672118802541. https://doi.org/10.1177/1120672118802541. [Epub ahead of print]
Pelletier JS, Miller D, Liang B & Capriotti JA (2011): In vitro efficacy of a povidone-iodine 0.4% and dexamethasone 0.1% suspension against ocular pathogens. J Cataract Refract Surg 37: 763-766.
Pepose JS, Ahuja A, Liu W, Narvekar A & Haque R (2018): Randomized, controlled, phase 2 trial of povidone-iodine/dexamethasone ophthalmic suspension for treatment of adenoviral conjunctivitis. Am J Ophthalmol 194: 7-15.
Pinna A, Sechi LA, Zanetti S & Carta F (2005): Detection of virulence factors in a corneal isolate of Klebsiella pneumoniae. Ophthalmology 112: 883-887.
Pinna A, Usai D, Sechi LA, Molicotti P, Zanetti S & Carta A (2008): Detection of virulence factors in Pseudomonas aeruginosa strains isolated from contact lens-associated corneal ulcers. Cornea 27: 320-326.
Pinna A, Usai D, Sechi LA, Zanetti S, Jesudasan NC, Thomas PA & Kaliamurthy J (2009): An outbreak of post-cataract surgery endophthalmitis caused by Pseudomonas aeruginosa. Ophthalmology 116: 2321-2326. e1-4.
Rutala WA (1996): APIC guideline for selection and use of disinfectants. 1994, 1995, and 1996 APIC Guidelines Committee. Association for Professionals in Infection Control and Epidemiology, Inc. Am J Infect Control 24: 313-342.
Rynerson JM & Perry HD (2016): DEBS - a unification theory for dry eye and blepharitis. Clin Ophthlmol 10: 2455-2467.
Safar A & Dellimore MC (2007): The effect of povidone iodine flush versus drops on conjunctival colonization before intravitreal injections. Int Ophthalmol 27: 307-312.
Sengupta J, Khetan A, Saha S, Banerjee D, Gangopadhyay N & Pal D (2012): Candida keratitis: emerging problem in India. Cornea 31: 371-375.
Szczotka-Flynn LB, Imamura Y, Chandra J, Yu C, Mukherjee PK, Pearlman E & Ghannoum MA (2009): Increased resistance of contact lens-related bacterial biofilms to antimicrobial activity of soft contact lens care solutions. Cornea 28: 918-926.
The European Society of Cataract and Refractive Surgeons (2013): ESCRS guidelines on prevention and treatment of endophthalmitis after cataract surgery. Available at: http://www.escrs. org/endophthalmitis/guidelines/ENGLISH.pdf (Accessed on 13 Aug 2019).
Yin VT, Weisbrod DJ, Eng KT et al. (2013): Antibiotic resistance of ocular surface flora with repeated use of a topical antibiotic after intravitreal injection. JAMA Ophthalmol 131: 456-461.
Zegans ME, Becker HI, Budzik J & O'Toole G (2002): The role of bacterial biofilms in ocular infections. DNA Cell Biol 21: 415-420.