Short-term results in infants with multiple left heart obstructive lesions.
Cardiac Surgical Procedures
/ adverse effects
Child, Preschool
Echocardiography
Female
Heart Defects, Congenital
/ diagnostic imaging
Heart Ventricles
/ abnormalities
Humans
Infant
Infant, Newborn
Male
Palliative Care
Recovery of Function
Retrospective Studies
Risk Factors
Time Factors
Treatment Outcome
Ventricular Function, Left
Ventricular Function, Right
Shone’s complex
congenital heart disease
echocardiography
left heart obstruction
surgical outcomes
Journal
Congenital heart disease
ISSN: 1747-0803
Titre abrégé: Congenit Heart Dis
Pays: United States
ID NLM: 101256510
Informations de publication
Date de publication:
Nov 2019
Nov 2019
Historique:
received:
26
04
2019
revised:
05
06
2019
accepted:
16
07
2019
pubmed:
7
9
2019
medline:
1
7
2020
entrez:
7
9
2019
Statut:
ppublish
Résumé
Deciding on a surgical pathway for neonates with ≥2 left heart obstructive lesions is complex. Predictors of the successful biventricular (2V) repair in these patients are poorly defined. The goal of our study was to identify patients who underwent the 2V repair and assess anatomic and echocardiographic predictors of success. Infants born between July 2015 and August 2017 with ≥2 left heart obstructive lesions with no prior interventions were identified (n = 19). Patients with aortic or mitral valve (MV) atresia and critical aortic stenosis were excluded. Initial echocardiograms were reviewed for aortic, MV, tricuspid valve annulus size, and left (LV) and right (RV) ventricle diastolic longitudinal dimensions. The valve morphology and presence of a ventricular septal defect (VSD) and coarctation were assessed. Clinical outcomes included successful 2V repair, complications, and repeat interventions or surgeries. Failed 2V repair was defined as a takedown to single ventricle (1V) physiology, cardiac transplantation, or death. For 2V repair, 14/19 patients were selected and for 1V, 5/19 patients were selected. Initial surgical procedures of the 2V group were simple coarctation repair (5), complex coarctation/arch reconstruction +/- septal defect closure (6), hybrid stage 1 (2), and none (1). Three of the 2V patients required reintervention in the first 90 days. The LV to RV diastolic longitudinal ratio >0.75 and mitral/tricuspid ratio of <0.8 were observed in 13/14 of the 2V patients. The LV:RV ratio and the aortic valve z score were significantly larger in the 2V group compared to the 1V group. All patients in the 1V group had a nonapex forming LV. There was no mortality with follow-up to three years of age. This study showed excellent short-term and midterm surgical results in the 2V population. The LV:RV diastolic longitudinal ratio may be a useful tool in the risk stratification of a successful 2V repair even in cases with a small MV.
Types de publication
Comparative Study
Journal Article
Langues
eng
Pagination
1193-1198Informations de copyright
© 2019 Wiley Periodicals, Inc.
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