Yangpumicins F and G, Enediyne Congeners from
Journal
Journal of natural products
ISSN: 1520-6025
Titre abrégé: J Nat Prod
Pays: United States
ID NLM: 7906882
Informations de publication
Date de publication:
27 09 2019
27 09 2019
Historique:
pubmed:
7
9
2019
medline:
5
11
2020
entrez:
7
9
2019
Statut:
ppublish
Résumé
Enediyne natural products are among the most cytotoxic small molecules and thus excellent payload candidates for the development of antibody-drug conjugates (ADCs). Here we report the isolation and structural elucidation of two new 10-membered anthraquinone-fused enediynes, yangpumicins (YPM) F (
Identifiants
pubmed: 31490685
doi: 10.1021/acs.jnatprod.9b00229
pmc: PMC7170010
mid: NIHMS1582470
doi:
Substances chimiques
Anti-Bacterial Agents
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2483-2488Subventions
Organisme : NIGMS NIH HHS
ID : R01 GM115575
Pays : United States
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