Hematopoietic-Extrinsic Cues Dictate Circadian Redistribution of Mature and Immature Hematopoietic Cells in Blood and Spleen.
CXCL12
bmal1
circadian rhythm
clock genes
cortisol
hematopoiesis
Journal
Cells
ISSN: 2073-4409
Titre abrégé: Cells
Pays: Switzerland
ID NLM: 101600052
Informations de publication
Date de publication:
05 09 2019
05 09 2019
Historique:
received:
02
08
2019
revised:
29
08
2019
accepted:
02
09
2019
entrez:
8
9
2019
pubmed:
8
9
2019
medline:
7
5
2020
Statut:
epublish
Résumé
Circadian oscillations in circulating leukocyte subsets including immature hematopoietic cells have been appreciated; the origin and nature of these alterations remain elusive. Our analysis of wild-type C57BL/6 mice under constant darkness confirmed circadian fluctuations of circulating leukocytes and clonogenic cells in blood and spleen but not bone marrow. Clock gene deficient
Identifiants
pubmed: 31491915
pii: cells8091033
doi: 10.3390/cells8091033
pmc: PMC6769956
pii:
doi:
Substances chimiques
ARNTL Transcription Factors
0
Bmal1 protein, mouse
0
Chemokine CXCL12
0
Cxcl12 protein, mouse
0
CLOCK Proteins
EC 2.3.1.48
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
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