2019 international clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer.


Journal

The Lancet. Oncology
ISSN: 1474-5488
Titre abrégé: Lancet Oncol
Pays: England
ID NLM: 100957246

Informations de publication

Date de publication:
10 2019
Historique:
received: 27 02 2019
revised: 02 05 2019
accepted: 07 05 2019
pubmed: 8 9 2019
medline: 23 6 2020
entrez: 8 9 2019
Statut: ppublish

Résumé

Venous thromboembolism (VTE) is the second leading cause of death in patients with cancer. These patients are at a high risk of VTE recurrence and bleeding during anticoagulant therapy. The International Initiative on Thrombosis and Cancer is an independent academic working group aimed at establishing a global consensus for the treatment and prophylaxis of VTE in patients with cancer. The International Initiative on Thrombosis and Cancer last updated its evidence-based clinical practice guidelines in 2016 with a free, web-based mobile phone application, which was subsequently endorsed by the International Society on Thrombosis and Haemostasis. The 2019 International Initiative on Thrombosis and Cancer clinical practice guidelines, which are based on a systematic review of the literature published up to December, 2018, are presented along with a Grading of Recommendations Assessment Development and Evaluation scale methods, with the support of the French National Cancer Institute. These guidelines were reviewed by an expanded international advisory committee and endorsed by the International Society on Thrombosis and Haemostasis. Results from head-to-head clinical trials that compared direct oral anticoagulant with low-molecular-weight heparin are also summarised, along with new evidence for the treatment and prophylaxis of VTE in patients with cancer.

Identifiants

pubmed: 31492632
pii: S1470-2045(19)30336-5
doi: 10.1016/S1470-2045(19)30336-5
pii:
doi:

Substances chimiques

Anticoagulants 0
Factor Xa Inhibitors 0
Heparin, Low-Molecular-Weight 0
Vitamin K 12001-79-5
Fondaparinux J177FOW5JL

Types de publication

Journal Article Practice Guideline Research Support, N.I.H., Extramural Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

e566-e581

Investigateurs

Walter Ageno (W)
Fernando Ajauro (F)
Kamal R Al-Aboudi (KR)
Thierry Alcindor (T)
Thierry Andre (T)
Pantep Angchaisuksiri (P)
Darko Antic (D)
Juan I Arcelus (JI)
Eric Assenat (E)
Kenneth A Bauer (KA)
Ali Bazarbachii (A)
Ilham Benzidia (I)
Jan Beyer-Westendorf (J)
Viktoria Bitsadze (V)
Dorit Blickstein (D)
Mark Blostein (M)
Isabel Bogalho (I)
Barbara Bournet (B)
Patricia Casais (P)
Antoine F Carpentier (AF)
Gabriela Cesarman-Maus (G)
Joydeep Chakbrabartty (J)
Hugo Clemente (H)
Jérôme Connault (J)
Ludovic Doucet (L)
Cécile Durant (C)
Joseph Emmerich (J)
Anna Falanga (A)
Clemens Feistritzer (C)
Carme Font (C)
Charles Francis (C)
Enrique Gallardo (E)
Thomas Gary (T)
Jean-Christophe Gris (JC)
Cecilia Guillermo (C)
Adrian Hij (A)
Russel D Hull (RD)
Takayuki IKezoe (T)
Luis Jara-Palomares (L)
Nigel S Key (NS)
Jamilya Khrizroeva (J)
Maral Koolian (M)
Florian Langer (F)
Claire Le Hello (C)
Ramón Lecumberri (R)
Lai Heng Lee (LH)
Howard Liebman (H)
Luisa Lopes Dos Santos (L)
Duarte Henrique Machado (DH)
Isabelle Madelaine (I)
Alexander Makatsariya (A)
Mario Mandala (M)
Anthony Marayevas (A)
Zora Marjanovic (Z)
Christine Marosi (C)
Ellis Martin (E)
Luis Meillon (L)
Emmanuel Messas (E)
Antonio Moreira (A)
Ahmet M Demir (AM)
Arlette Ndour (A)
Michel Nguessan (M)
Remedios Otero-Candelera (R)
Vanessa Pachon Olmos (V)
Ana Pais (A)
Florian Posch (F)
Matthias Preusser (M)
Hanno Riess (H)
Marc Righini (M)
Cynthia Rothschild (C)
Andre Roussin (A)
José Antonio Rueda-Camino (JA)
Pedro Ruiz-Artacho (P)
Sanjith Saseedharan (S)
Ali Shamseddine (A)
Gerald Soff (G)
Hans Stricker (H)
Vicky Tagalakis (V)
Ali Taher (A)
Toutou Toussaint (T)
Javier Trujillo-Santos (J)
Stéphane Villiers (S)
Raymond Wong (R)
Norizaku Yamada (N)

Informations de copyright

Copyright © 2019 Elsevier Ltd. All rights reserved.

Auteurs

Dominique Farge (D)

Autoimmune and Vascular Disease Unit, Internal Medicine (UF04), Center of Reference for Rare Systemic Autoimmune Diseases (FAI2R), Université de Paris, Paris, France; Department of Medicine, McGill University, Montreal, QC, Canada. Electronic address: itaccme@gmail.com.

Corinne Frere (C)

Department of Haematology, Sorbonne Université, UMRS 1166, Assistance Publique Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Paris, France.

Jean M Connors (JM)

Hematology Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Cihan Ay (C)

Clinical Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.

Alok A Khorana (AA)

Cleveland Clinic, Taussig Cancer Institute and Case Comprehensive Cancer Center, Cleveland, OH, USA.

Andres Munoz (A)

Medical Oncology Department, Hospital General Universitario Gregorio Maranon, Universidad Complutense, Madrid, Spain.

Benjamin Brenner (B)

Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus, Haifa, Israel.

Ajay Kakkar (A)

Thrombosis Research Institute and University College London, London, UK.

Hanadi Rafii (H)

Eurocord, Assistance Publique-Hôpitaux de Paris, Saint-Louis Hospital, Université de Paris, Paris, France.

Susan Solymoss (S)

Department of Medicine, McGill University, Montreal, QC, Canada.

Dialina Brilhante (D)

Francisco Gentil Portuguese Institute of Oncology, Lisbon Center, Lisbon, Portugal.

Manuel Monreal (M)

Department of Internal Medicine, Hospital Germans Trias i Pujol, Universidad Católica de Murcia, Badalona, Barcelona, Spain.

Henri Bounameaux (H)

Division of Angiology and Hemostasis, Faculty of Medicine, University Hospitals of Geneva, Geneva, Switzerland.

Ingrid Pabinger (I)

Clinical Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.

James Douketis (J)

Department of Medicine, McMaster University, Hamilton ON, Canada.

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