Acid sphingomyelinase regulates T
T cells
TH2
acid sphingomyelinase
allergic disease
asthmatic response
Journal
Allergy
ISSN: 1398-9995
Titre abrégé: Allergy
Pays: Denmark
ID NLM: 7804028
Informations de publication
Date de publication:
03 2020
03 2020
Historique:
received:
19
02
2019
revised:
01
08
2019
accepted:
19
08
2019
pubmed:
9
9
2019
medline:
15
5
2021
entrez:
9
9
2019
Statut:
ppublish
Résumé
Allergic diseases and especially allergic asthma are widespread diseases with high prevalence in childhood, but also in adults. Acid sphingomyelinase (ASM) is a key regulator of the sphingolipid pathway. Previous studies defined the association of ASM with the pathogenesis of T To determine the role of Asm under baseline conditions, wild-type (WT) and Asm At baseline, Asm Asm deficiency could induce higher numbers of T
Sections du résumé
BACKGROUND
Allergic diseases and especially allergic asthma are widespread diseases with high prevalence in childhood, but also in adults. Acid sphingomyelinase (ASM) is a key regulator of the sphingolipid pathway. Previous studies defined the association of ASM with the pathogenesis of T
METHODS
To determine the role of Asm under baseline conditions, wild-type (WT) and Asm
RESULTS
At baseline, Asm
CONCLUSION
Asm deficiency could induce higher numbers of T
Substances chimiques
Cytokines
0
Ovalbumin
9006-59-1
Sphingomyelin Phosphodiesterase
EC 3.1.4.12
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
603-615Informations de copyright
© 2020 The Authors. Allergy published by John Wiley & Sons Ltd.
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