[Pyoderma gangrenosum and systemic lupus erythematosus: A rare association].

Pyoderma gangrenosum et lupus érythémateux systémique : une association rare.

Journal

La Revue de medecine interne
ISSN: 1768-3122
Titre abrégé: Rev Med Interne
Pays: France
ID NLM: 8101383

Informations de publication

Date de publication:
Jan 2020
Historique:
received: 05 06 2019
revised: 03 08 2019
accepted: 06 08 2019
pubmed: 10 9 2019
medline: 18 11 2020
entrez: 10 9 2019
Statut: ppublish

Résumé

Pyoderma gangrenosum (PG) is a neutrophilic dermatosis that is traditionally associated with systemic disorders such as chronic inflammatory bowel diseases, rheumatoid arthritis and malignant hematologic disorders. Its association with systemic lupus erythematosus (SLE) is rare and not well known. We report a case of this association with a review of the literature. A 43-year-old female patient, followed for 4 years for SLE, presented a deep ulceration of the anterior face of the left thigh with inflammatory borders, an ulcerated nodule of the right shoulder and four small ulcerations of the back of the right hand. The biopsy of the ulceration of the left thigh concluded to PG. The patient was treated by corticosteroids with complete healing of lesions. The prognosis of lupus does not seem to be aggravated by PG and the treatments of a SLE flare are usually enough for treating associated PG.

Identifiants

pubmed: 31495525
pii: S0248-8663(19)30618-6
doi: 10.1016/j.revmed.2019.08.001
pii:
doi:

Substances chimiques

Glucocorticoids 0
Prednisone VB0R961HZT

Types de publication

Case Reports Journal Article

Langues

fre

Sous-ensembles de citation

IM

Pagination

54-57

Informations de copyright

Copyright © 2019 Société Nationale Française de Médecine Interne (SNFMI). Published by Elsevier Masson SAS. All rights reserved.

Auteurs

O Magdoud (O)

Dermatology department, La Rabta Hospital, Tunis, Tunisia. Electronic address: oumayma.magdoud@gmail.com.

A Souissi (A)

Dermatology department, La Rabta Hospital, Tunis, Tunisia.

I Chelly (I)

Pathology department, La Rabta Hospital, Tunis, Tunisia.

S Haouet (S)

Pathology department, La Rabta Hospital, Tunis, Tunisia.

M Mokni (M)

Dermatology department, La Rabta Hospital, Tunis, Tunisia.

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Classifications MeSH