An Ancient Harappan Genome Lacks Ancestry from Steppe Pastoralists or Iranian Farmers.
Harappan Civilization
Indus Valley Civilization
South Asia
ancient DNA
anthropology
archaeology
population genetics
Journal
Cell
ISSN: 1097-4172
Titre abrégé: Cell
Pays: United States
ID NLM: 0413066
Informations de publication
Date de publication:
17 10 2019
17 10 2019
Historique:
received:
09
08
2019
revised:
26
08
2019
accepted:
27
08
2019
pubmed:
10
9
2019
medline:
28
5
2020
entrez:
10
9
2019
Statut:
ppublish
Résumé
We report an ancient genome from the Indus Valley Civilization (IVC). The individual we sequenced fits as a mixture of people related to ancient Iranians (the largest component) and Southeast Asian hunter-gatherers, a unique profile that matches ancient DNA from 11 genetic outliers from sites in Iran and Turkmenistan in cultural communication with the IVC. These individuals had little if any Steppe pastoralist-derived ancestry, showing that it was not ubiquitous in northwest South Asia during the IVC as it is today. The Iranian-related ancestry in the IVC derives from a lineage leading to early Iranian farmers, herders, and hunter-gatherers before their ancestors separated, contradicting the hypothesis that the shared ancestry between early Iranians and South Asians reflects a large-scale spread of western Iranian farmers east. Instead, sampled ancient genomes from the Iranian plateau and IVC descend from different groups of hunter-gatherers who began farming without being connected by substantial movement of people.
Identifiants
pubmed: 31495572
pii: S0092-8674(19)30967-5
doi: 10.1016/j.cell.2019.08.048
pmc: PMC6800651
mid: NIHMS1538584
pii:
doi:
Substances chimiques
DNA, Ancient
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
729-735.e10Subventions
Organisme : Howard Hughes Medical Institute
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM100233
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM007753
Pays : United States
Informations de copyright
Copyright © 2019 Elsevier Inc. All rights reserved.
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