Cytomegalovirus renal infection: Rare manifestation of a common post-transplant viral infection-A case series.
Adolescent
Adult
Allografts
/ immunology
Antiviral Agents
/ administration & dosage
Biopsy
Cytomegalovirus
/ immunology
Cytomegalovirus Infections
/ diagnosis
Humans
Kidney
/ immunology
Kidney Failure, Chronic
/ surgery
Kidney Transplantation
/ adverse effects
Male
Middle Aged
Transplant Recipients
Treatment Outcome
Valganciclovir
/ administration & dosage
Cytomegalovirus renal infection
kidney transplant
Journal
Transplant infectious disease : an official journal of the Transplantation Society
ISSN: 1399-3062
Titre abrégé: Transpl Infect Dis
Pays: Denmark
ID NLM: 100883688
Informations de publication
Date de publication:
Dec 2019
Dec 2019
Historique:
received:
12
02
2019
revised:
19
07
2019
accepted:
25
08
2019
pubmed:
10
9
2019
medline:
1
5
2020
entrez:
10
9
2019
Statut:
ppublish
Résumé
Cytomegalovirus is the most common viral infection in organ transplant recipients that usually affects the brain, lungs, liver, and gastrointestinal tract. Renal involvement of Cytomegalovirus (CMV) is otherwise rare. We present six cases of biopsy-proven CMV renal infection. Five out of the six patients had detectable CMV viremia. Kidney biopsy revealed glomerulopathy in four cases and tubulointerstitial involvement in two cases. All patients exhibited decline in renal function at the onset of infection. Four out of six patients had improvement of renal function following treatment of CMV disease. To date, this is the largest case series of pure biopsy-proven CMV renal infection described in a single center.
Substances chimiques
Antiviral Agents
0
Valganciclovir
GCU97FKN3R
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e13169Informations de copyright
© 2019 Wiley Periodicals, Inc.
Références
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