Assessment of Inner Retinal Layers and Choroidal Thickness in Type 1 Diabetes Mellitus: A Cross-Sectional Study.

choroid diabetic retinopathy ganglion cell layer retinal nerve fibre layer type 1 diabetes

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
08 Sep 2019
Historique:
received: 30 07 2019
revised: 29 08 2019
accepted: 04 09 2019
entrez: 11 9 2019
pubmed: 11 9 2019
medline: 11 9 2019
Statut: epublish

Résumé

Recent studies have shown that retinal neurodegeneration may precede visible vascular changes in diabetic retinopathy (DR). In addition, the relationship of choroidal thickness (CT) with DR stage is not well defined. To assess the inner retinal and choroidal structural changes in type 1 diabetic subjects (T1D), a cross-sectional study was conducted in 242 T1D patients and in 69 age-matched, non-diabetic individuals. The nasal retinal nerve fibre layer (RNFL) thickness was lower in T1D patients without DR (

Identifiants

DOI: 10.3390/jcm8091412 PMID: 31500371 PMC: PMC6780763
pubmed: 31500371
pii: jcm8091412
doi: 10.3390/jcm8091412
pmc: PMC6780763
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Instituto de Salud Carlos III
ID : PI15/0625
Organisme : Instituto de Salud Carlos III
ID : PI12/0183

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Auteurs

Marc Carbonell (M)

Department of Ophthalmology, University Hospital Germans Trias i Pujol, 08916 Badalona, Spain. marc_carbonell@hotmail.com.
Department of Surgery, Barcelona Autonomous University (UAB), 08035 Barcelona, Spain. marc_carbonell@hotmail.com.

Núria Alonso (N)

Department of Endocrinology and Nutrition, University Hospital and Health Science Research Institute Germans Trias i Pujol, 08916 Badalona, Spain. nalonso32416@yahoo.es.
Centre for Biomedical Research on Diabetes and Associated Metabolic Diseases (CIBERDEM), 08907 Barcelona, Spain. nalonso32416@yahoo.es.
Department of Medicine, Barcelona Autonomous University (UAB), 08035 Barcelona, Spain. nalonso32416@yahoo.es.

Esmeralda Castelblanco (E)

Centre for Biomedical Research on Diabetes and Associated Metabolic Diseases (CIBERDEM), 08907 Barcelona, Spain. esmeraldacas@gmail.com.
Department of Endocrinology & Nutrition, Hospital de la Santa Creu i Sant Pau & Institut d'Investigació Biomèdica Sant Pau (IIB Sant Pau), 08041 Barcelona, Spain. esmeraldacas@gmail.com.
DAP-Cat Group, Unitat de Suport a la Recerca Barcelona, Fundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), 08025 Barcelona, Spain. esmeraldacas@gmail.com.
ORCID: 0000-0002-2061-6270

Jordi Real (J)

Centre for Biomedical Research on Diabetes and Associated Metabolic Diseases (CIBERDEM), 08907 Barcelona, Spain. jordireal@gmail.com.
DAP-Cat Group, Unitat de Suport a la Recerca Barcelona, Fundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), 08025 Barcelona, Spain. jordireal@gmail.com.

Anna Ramírez-Morros (A)

Department of Endocrinology and Nutrition, University Hospital and Health Science Research Institute Germans Trias i Pujol, 08916 Badalona, Spain. amramirezmorros@gmail.com.

Rafael Simó (R)

Centre for Biomedical Research on Diabetes and Associated Metabolic Diseases (CIBERDEM), 08907 Barcelona, Spain. rafael.simo@vhir.org.
Department of Endocrinology and Nutrition, Hospital Universitari Vall d'Hebron, Diabetes and Metabolism Research Unit, Vall d'Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, 08035 Barcelona, Catalonia, Spain. rafael.simo@vhir.org.
ORCID: 0000-0003-0475-3096

Cristina Hernández (C)

Centre for Biomedical Research on Diabetes and Associated Metabolic Diseases (CIBERDEM), 08907 Barcelona, Spain. cristina.hernandez@vhir.org.
Department of Endocrinology and Nutrition, Hospital Universitari Vall d'Hebron, Diabetes and Metabolism Research Unit, Vall d'Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, 08035 Barcelona, Catalonia, Spain. cristina.hernandez@vhir.org.
ORCID: 0000-0002-3109-1721

Carme Jurjo (C)

Department of Ophthalmology, University Hospital Arnau de Vilanova, 25198 Lleida, Spain. carmenjurjo@gmail.com.
Biomedical Research Institute of Lleida (IRBLleida) & University of Lleida, 25198 Lleida, Spain. carmenjurjo@gmail.com.

Alícia Traveset (A)

Department of Ophthalmology, University Hospital Arnau de Vilanova, 25198 Lleida, Spain. atravesetm@gmail.com.
Biomedical Research Institute of Lleida (IRBLleida) & University of Lleida, 25198 Lleida, Spain. atravesetm@gmail.com.

Xavier Valldeperas (X)

Department of Ophthalmology, University Hospital Germans Trias i Pujol, 08916 Badalona, Spain. xvalldeperas@gmail.com.
Department of Surgery, Barcelona Autonomous University (UAB), 08035 Barcelona, Spain. xvalldeperas@gmail.com.

Dídac Mauricio (D)

Centre for Biomedical Research on Diabetes and Associated Metabolic Diseases (CIBERDEM), 08907 Barcelona, Spain. didacmauricio@gmail.com.
Department of Medicine, Barcelona Autonomous University (UAB), 08035 Barcelona, Spain. didacmauricio@gmail.com.
Department of Endocrinology & Nutrition, Hospital de la Santa Creu i Sant Pau & Institut d'Investigació Biomèdica Sant Pau (IIB Sant Pau), 08041 Barcelona, Spain. didacmauricio@gmail.com.
DAP-Cat Group, Unitat de Suport a la Recerca Barcelona, Fundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), 08025 Barcelona, Spain. didacmauricio@gmail.com.
Biomedical Research Institute of Lleida (IRBLleida) & University of Lleida, 25198 Lleida, Spain. didacmauricio@gmail.com.
ORCID: 0000-0002-2868-0250

Classifications MeSH