The expression of galectin-3 in breast cancer and its association with chemoresistance: a systematic review of the literature.
Breast cancer
Chemoresistance
Chemosensitivity
Drug-induced apoptosis
Galectin-3
Journal
Archives of gynecology and obstetrics
ISSN: 1432-0711
Titre abrégé: Arch Gynecol Obstet
Pays: Germany
ID NLM: 8710213
Informations de publication
Date de publication:
11 2019
11 2019
Historique:
received:
21
04
2019
accepted:
04
09
2019
pubmed:
11
9
2019
medline:
6
5
2020
entrez:
11
9
2019
Statut:
ppublish
Résumé
Galectin-3 is a M Scopus and PubMed databases were searched on 26 November 2018 using the following combination of keywords: (galectin-3 OR gal-3 OR LGALS3) AND (breast cancer) AND (chemoresistance OR (drug resistance) OR chemosensitivity). All the articles in English, regardless the time of publication, text availability and species included were initially accepted. In the majority of the included studies, the expression of galectin-3 had a protective role in cell survival via different pathways such as the response to DNA damage and repair or the inhibition of apoptosis after treatment with a chemotherapeutic agent. Galectin-3 expression in breast tumors might be an important factor in the selection of the most suitable treatment.
Identifiants
pubmed: 31502061
doi: 10.1007/s00404-019-05292-9
pii: 10.1007/s00404-019-05292-9
doi:
Substances chimiques
Antineoplastic Agents
0
Blood Proteins
0
Galectin 3
0
Galectins
0
LGALS3 protein, human
0
Types de publication
Journal Article
Systematic Review
Langues
eng
Sous-ensembles de citation
IM