Ceftaroline-associated Encephalopathy in Patients With Severe Renal Impairment.
ceftaroline
drug toxicity
encephalopathy
renal failure
Journal
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
ISSN: 1537-6591
Titre abrégé: Clin Infect Dis
Pays: United States
ID NLM: 9203213
Informations de publication
Date de publication:
15 04 2020
15 04 2020
Historique:
received:
26
04
2019
accepted:
27
08
2019
pubmed:
11
9
2019
medline:
7
1
2021
entrez:
11
9
2019
Statut:
ppublish
Résumé
Encephalopathy complicates beta-lactam therapy, particularly with impaired renal function, though no studies have reported ceftaroline-associated encephalopathy. Among 28 patients with estimated glomerular filtration rates <30 mL/min who received ≥5 days of ceftaroline, 3 developed encephalopathy. Ceftaroline, when dosed supra-therapeutically for serious infections, may be a cause of antibiotic-associated encephalopathy.
Identifiants
pubmed: 31504321
pii: 5556474
doi: 10.1093/cid/ciz857
pmc: PMC7156771
doi:
Substances chimiques
Anti-Bacterial Agents
0
Cephalosporins
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
2002-2004Informations de copyright
© The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.
Références
Neurology. 2016 Mar 8;86(10):963-71
pubmed: 26888997
Open Forum Infect Dis. 2017 May 02;4(2):ofx084
pubmed: 28702467
Drug Saf. 2017 Dec;40(12):1171-1198
pubmed: 28755095
Clin Pharmacol Ther. 1981 Aug;30(2):239-45
pubmed: 7249508