Subtemporal Transtentorial Approach in Mesencephalic and Perimesencephalic Lesions in Children-A Series of 20 Patients.

Brain stem tumors Cavernoma Craniopharyngioma Dermoid Pediatric neurosurgery Subtemporal approach

Journal

Operative neurosurgery (Hagerstown, Md.)
ISSN: 2332-4260
Titre abrégé: Oper Neurosurg (Hagerstown)
Pays: United States
ID NLM: 101635417

Informations de publication

Date de publication:
01 04 2020
Historique:
received: 14 11 2018
accepted: 08 06 2019
pubmed: 11 9 2019
medline: 22 6 2021
entrez: 11 9 2019
Statut: ppublish

Résumé

Midbrain and surrounding areas are among the most difficult regions to surgically approach in neurosurgery. The subtemporal approach is a well-known neurosurgical approach that is rarely described in children. To assess the feasibility, advantages, and disadvantages of subtemporal approach in children. A total of 20 pediatric patients with intra-axial tumors involving the lateral midbrain or superior cerebellar peduncle or with extra-axial tumors in the middle incisural space/Meckel cave underwent subtemporal transtentorial approaches with the aim to remove (16 cases) or biopsy (4 cases) their lesions. These cases were retrospectively reviewed and the surgical approach described. Total resection was achieved in 11 patients. In the 4 patients who underwent biopsies, a diagnosis was obtained. A total of 5 patients presented non-neoplastic lesions (dermoid tumors or cavernomas). A total of 9 patients harbored low-grade tumors and 6 high-grade tumors. Patients with low-grade tumors and non-neoplastic lesions are all alive with no evidence of disease or stable residue. Four patients affected by high grade tumors died. No patient suffered permanent neurological deficits related to the surgical approach. Three patients presented temporary neurological deficits following the procedure: one case of strabismus, one case of aphasia and hemiparesis, secondary to delayed, transient thrombosis of the Labbé vein, and 1 case of trigeminal neuralgia. The subtemporal approach represents a feasible approach for mesencephalic and perimesencephalic lesions in children. It provides an ample and direct access, with excellent outcomes and acceptable postoperative morbidity.

Sections du résumé

BACKGROUND
Midbrain and surrounding areas are among the most difficult regions to surgically approach in neurosurgery. The subtemporal approach is a well-known neurosurgical approach that is rarely described in children.
OBJECTIVE
To assess the feasibility, advantages, and disadvantages of subtemporal approach in children.
METHODS
A total of 20 pediatric patients with intra-axial tumors involving the lateral midbrain or superior cerebellar peduncle or with extra-axial tumors in the middle incisural space/Meckel cave underwent subtemporal transtentorial approaches with the aim to remove (16 cases) or biopsy (4 cases) their lesions. These cases were retrospectively reviewed and the surgical approach described.
RESULTS
Total resection was achieved in 11 patients. In the 4 patients who underwent biopsies, a diagnosis was obtained. A total of 5 patients presented non-neoplastic lesions (dermoid tumors or cavernomas). A total of 9 patients harbored low-grade tumors and 6 high-grade tumors. Patients with low-grade tumors and non-neoplastic lesions are all alive with no evidence of disease or stable residue. Four patients affected by high grade tumors died. No patient suffered permanent neurological deficits related to the surgical approach. Three patients presented temporary neurological deficits following the procedure: one case of strabismus, one case of aphasia and hemiparesis, secondary to delayed, transient thrombosis of the Labbé vein, and 1 case of trigeminal neuralgia.
CONCLUSION
The subtemporal approach represents a feasible approach for mesencephalic and perimesencephalic lesions in children. It provides an ample and direct access, with excellent outcomes and acceptable postoperative morbidity.

Identifiants

pubmed: 31504862
pii: 5560168
doi: 10.1093/ons/opz254
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

349-362

Informations de copyright

Copyright © 2019 by the Congress of Neurological Surgeons.

Auteurs

Pietro Spennato (P)

Department of Pediatric Neurosurgery, Santobono-Pausilipon Children's Hospital, Naples, Italy.

Carmela Chiaramonte (C)

Department of Pediatric Neurosurgery, Santobono-Pausilipon Children's Hospital, Naples, Italy.

Carmela Russo (C)

Department of Pediatric Neuroradiology, Santobono-Pausilipon Children's Hospital, Naples, Italy.

Nicola Onorini (N)

Department of Pediatric Neurosurgery, Santobono-Pausilipon Children's Hospital, Naples, Italy.
Neurosurgery Unit, University of Brescia, Brescia, Italy.

Giuseppe Mirone (G)

Department of Pediatric Neurosurgery, Santobono-Pausilipon Children's Hospital, Naples, Italy.

Federica Mazio (F)

Department of Pediatric Neuroradiology, Santobono-Pausilipon Children's Hospital, Naples, Italy.

Giuliana Di Martino (G)

Department of Pediatric Neurosurgery, Santobono-Pausilipon Children's Hospital, Naples, Italy.

Raffaele Stefano Parlato (RS)

Department of Pediatric Neurosurgery, Santobono-Pausilipon Children's Hospital, Naples, Italy.

Giuseppe Cinalli (G)

Department of Pediatric Neurosurgery, Santobono-Pausilipon Children's Hospital, Naples, Italy.

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