Pulmonary Hypertension in Patients Eligible for Transcatheter Mitral Valve Repair: Prognostic Impact and Clinical Implications.

MitraClip Mitral regurgitation Pulmonary hypertension Transcatheter mitral valve repair Transcutaneous mitral valve repair

Journal

Current treatment options in cardiovascular medicine
ISSN: 1092-8464
Titre abrégé: Curr Treat Options Cardiovasc Med
Pays: United States
ID NLM: 9815942

Informations de publication

Date de publication:
10 Sep 2019
Historique:
entrez: 12 9 2019
pubmed: 12 9 2019
medline: 12 9 2019
Statut: epublish

Résumé

Transcatheter edge-to-edge mitral valve repair (TMVr) has been increasingly used in the treatment of patients with severe symptomatic mitral regurgitation who are at high or prohibitive risk for surgical intervention. Pre-existing pulmonary hypertension is known to pertain worse prognosis for patients who are undergoing surgical intervention. The aim of this review is to discuss the current literature on the effects of pulmonary hypertension on the transcatheter edge-to-edge mitral valve repair outcomes. Large registry data in patients undergoing TMVr for treatment of severe mitral regurgitation reveal a significant negative impact of baseline pulmonary hypertension on post-procedural outcomes. Pulmonary hypertension is associated with increased mortality and heart failure readmissions in patients undergoing TMVr using MitraClip. Further prospective studies are needed to determine whether earlier intervention will improve clinical outcomes.

Identifiants

pubmed: 31506851
doi: 10.1007/s11936-019-0768-6
pii: 10.1007/s11936-019-0768-6
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

60

Références

J Am Coll Cardiol. 2001 Jan;37(1):183-8
pubmed: 11153735
J Am Soc Echocardiogr. 2006 Aug;19(8):1051-5
pubmed: 16880102
Lancet. 2006 Sep 16;368(9540):1005-11
pubmed: 16980116
J Am Coll Cardiol. 2008 Apr 29;51(17):1692-701
pubmed: 18436122
EuroIntervention. 2009 Jan;4(4):437-42
pubmed: 19284064
J Cardiothorac Vasc Anesth. 2009 Jun;23(3):298-305
pubmed: 19303325
Heart. 2010 Aug;96(16):1311-7
pubmed: 20659951
Eur Heart J. 2011 Mar;32(6):751-9
pubmed: 20829213
J Thorac Cardiovasc Surg. 2011 Oct;142(4):783-92
pubmed: 21397266
N Engl J Med. 2011 Apr 14;364(15):1395-406
pubmed: 21463154
J Thorac Cardiovasc Surg. 2011 Dec;142(6):1439-52
pubmed: 21962906
Eur J Heart Fail. 2013 Aug;15(8):868-76
pubmed: 23512095
J Am Coll Cardiol. 2013 Sep 17;62(12):1052-1061
pubmed: 23747789
JAMA. 2013 Aug 14;310(6):609-16
pubmed: 23942679
J Am Soc Echocardiogr. 2014 Jan;27(1):24-31.e1
pubmed: 24161483
J Am Coll Cardiol. 2013 Dec 24;62(25 Suppl):D100-8
pubmed: 24355634
Anaesthesia. 2014 Aug;69(8):860-7
pubmed: 24801455
J Am Heart Assoc. 2014 Aug 07;3(4):null
pubmed: 25103202
Am J Cardiol. 2014 Dec 1;114(11):1735-9
pubmed: 25306555
JACC Cardiovasc Imaging. 2015 Jan;8(1):83-99
pubmed: 25592699
J Am Coll Cardiol. 2015 Feb 10;65(5):452-61
pubmed: 25660923
JACC Cardiovasc Interv. 2015 Mar;8(3):450-459
pubmed: 25703879
J Am Coll Cardiol. 2015 Dec 29;66(25):2844-2854
pubmed: 26718672
J Am Coll Cardiol. 2016 Jun 28;67(25):2952-61
pubmed: 27339493
J Am Coll Cardiol. 2016 Jul 5;68(1):128-9
pubmed: 27364056
Circulation. 2017 Jan 17;135(3):297-314
pubmed: 28093494
J Am Coll Cardiol. 2017 Jul 11;70(2):252-289
pubmed: 28315732
JACC Cardiovasc Interv. 2017 May 8;10(9):931-939
pubmed: 28473116
JACC Cardiovasc Interv. 2017 May 8;10(9):940-941
pubmed: 28473117
Am J Cardiol. 2017 Aug 15;120(4):662-669
pubmed: 28673638
Am J Cardiol. 2018 Feb 15;121(4):475-479
pubmed: 29268934
Eur Heart J. 2018 Apr 14;39(15):1255-1264
pubmed: 29281101
Eur J Heart Fail. 2018 Mar;20(3):585-594
pubmed: 29575435
N Engl J Med. 2018 Dec 13;379(24):2297-2306
pubmed: 30145927
N Engl J Med. 2018 Dec 13;379(24):2307-2318
pubmed: 30280640
Catheter Cardiovasc Interv. 2019 Jul 1;94(1):E30-E36
pubmed: 30506974

Auteurs

Evin Yucel (E)

Cardiac Ultrasound Laboratory, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St, Yawkey 5E, Boston, MA, 02114, USA. eyucel@partners.org.

Rasha Al-Bawardy (R)

Cardiac Catheterization Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

Philippe B Bertrand (PB)

Cardiac Ultrasound Laboratory, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St, Yawkey 5E, Boston, MA, 02114, USA.

Classifications MeSH