Body mass index and serum lipid profile: Association with atopic dermatitis in a paediatric population.
Adolescent
Body Mass Index
Case-Control Studies
Child
Child, Preschool
Cholesterol, HDL
/ blood
Cholesterol, LDL
/ blood
Cross-Sectional Studies
Dermatitis, Atopic
/ blood
Dyslipidemias
/ epidemiology
Female
Humans
Infant
Infant, Newborn
Male
Obesity
/ epidemiology
Prospective Studies
Spain
Triglycerides
/ blood
atopic dermatitis
body mass index
dyslipidemia
metabolic syndrome
obesity
overweight
Journal
The Australasian journal of dermatology
ISSN: 1440-0960
Titre abrégé: Australas J Dermatol
Pays: Australia
ID NLM: 0135232
Informations de publication
Date de publication:
Feb 2020
Feb 2020
Historique:
received:
17
03
2019
accepted:
05
08
2019
pubmed:
12
9
2019
medline:
15
12
2020
entrez:
12
9
2019
Statut:
ppublish
Résumé
The association between atopic dermatitis, body weight and serum lipid levels is not well known, and very few studies have examined this relationship in children. Children (n = 239) under 14 years old participated in this prospective cross-sectional study. The following variables were recorded: age, gender, weight, height, atopic dermatitis severity, serum levels of total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglycerides. Mean body mass index was slightly higher in atopic dermatitis patients than healthy controls and significantly higher in atopic dermatitis patients aged 0-2 years (atopic dermatitis, 16.7 ± 4.6; controls, 15.7 ± 1.3; P = 0.04) and 12-14 years (atopic dermatitis, 24.9 ± 5.3; controls, 20.6 ± 3.4; P = 0.03). Among atopic dermatitis patients, body mass index was significantly higher in those with severe atopic dermatitis in the 9-12 (P = 0.03) and 12-14 (P = 0.01) years groups. Mean serum lipid levels were higher in patients with severe atopic dermatitis than in the atopic dermatitis group as a whole. These differences reached statistical significance for total cholesterol (P = 0.04) and triglycerides (P = 0.02). The prevalence of overweight, obesity and dyslipidemia is greater in children with atopic dermatitis than in age-matched healthy counterparts.
Sections du résumé
BACKGROUND/OBJECTIVES
OBJECTIVE
The association between atopic dermatitis, body weight and serum lipid levels is not well known, and very few studies have examined this relationship in children.
METHODS
METHODS
Children (n = 239) under 14 years old participated in this prospective cross-sectional study. The following variables were recorded: age, gender, weight, height, atopic dermatitis severity, serum levels of total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglycerides.
RESULTS
RESULTS
Mean body mass index was slightly higher in atopic dermatitis patients than healthy controls and significantly higher in atopic dermatitis patients aged 0-2 years (atopic dermatitis, 16.7 ± 4.6; controls, 15.7 ± 1.3; P = 0.04) and 12-14 years (atopic dermatitis, 24.9 ± 5.3; controls, 20.6 ± 3.4; P = 0.03). Among atopic dermatitis patients, body mass index was significantly higher in those with severe atopic dermatitis in the 9-12 (P = 0.03) and 12-14 (P = 0.01) years groups. Mean serum lipid levels were higher in patients with severe atopic dermatitis than in the atopic dermatitis group as a whole. These differences reached statistical significance for total cholesterol (P = 0.04) and triglycerides (P = 0.02).
CONCLUSION
CONCLUSIONS
The prevalence of overweight, obesity and dyslipidemia is greater in children with atopic dermatitis than in age-matched healthy counterparts.
Substances chimiques
Cholesterol, HDL
0
Cholesterol, LDL
0
Triglycerides
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e60-e64Informations de copyright
© 2019 The Australasian College of Dermatologists.
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