Food allergy-related concerns during the transition to self-management.
Age
Food allergy
Gender
Health-related quality of life
Journal
Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology
ISSN: 1710-1484
Titre abrégé: Allergy Asthma Clin Immunol
Pays: England
ID NLM: 101244313
Informations de publication
Date de publication:
2019
2019
Historique:
received:
05
06
2019
accepted:
28
08
2019
entrez:
12
9
2019
pubmed:
12
9
2019
medline:
12
9
2019
Statut:
epublish
Résumé
Compared to non-allergic individuals, food allergic individuals have impaired health-related quality of life (HRQL). However, effects of gender and age are unclear. The objective of our study was to describe associations between allergies to common foods and HRQL with consideration to gender and age. Adolescents and adults (N = 137; 49.6% males) with specialist-diagnosed allergy to milk, egg and/or wheat completed age-appropriate versions of the Food Allergy Quality of Life Questionnaire (FAQLQ). We pooled common questions and calculated overall- and domain-specific HRQL in association with number and severity of symptoms and time elapse since worst reaction. In the entire study population, HRQL was not affected by gender or age, whereas gender-specific age categories affected HRQL among males only. For example, males 18-39 years had worse overall- (β = 0.77; 95% CI 0.08-1.45) and domain-specific HRQL vs. males < 18 years. Among participants with 1-3 food allergy symptoms, no associations were found. Among participants with 4-6 symptoms, the domain allergen avoidance and dietary restrictions was worse among older participants (e.g. 40+ years: β = 0.71; 95% CI 0.05-1.37 vs. < 18 years), and males 18-39 vs. < 18 years. Among participants with severe symptoms, females vs. males, and participants 18-39 vs. < 18 years had worse HRQL. At least 4 years since worst reaction was associated with worse HRQL for participants 40+ years vs. < 18 years, and older males vs. males < 18 years. Nearly all differences exceeded the clinical relevance threshold of ≥ 0.5. Associations between allergies to common foods and HRQL are affected by gender and age. Most affected are males 18-39 years. Among females, HRQL is more stable across age groups.
Sections du résumé
BACKGROUND
BACKGROUND
Compared to non-allergic individuals, food allergic individuals have impaired health-related quality of life (HRQL). However, effects of gender and age are unclear. The objective of our study was to describe associations between allergies to common foods and HRQL with consideration to gender and age.
METHODS
METHODS
Adolescents and adults (N = 137; 49.6% males) with specialist-diagnosed allergy to milk, egg and/or wheat completed age-appropriate versions of the Food Allergy Quality of Life Questionnaire (FAQLQ). We pooled common questions and calculated overall- and domain-specific HRQL in association with number and severity of symptoms and time elapse since worst reaction.
RESULTS
RESULTS
In the entire study population, HRQL was not affected by gender or age, whereas gender-specific age categories affected HRQL among males only. For example, males 18-39 years had worse overall- (β = 0.77; 95% CI 0.08-1.45) and domain-specific HRQL vs. males < 18 years. Among participants with 1-3 food allergy symptoms, no associations were found. Among participants with 4-6 symptoms, the domain allergen avoidance and dietary restrictions was worse among older participants (e.g. 40+ years: β = 0.71; 95% CI 0.05-1.37 vs. < 18 years), and males 18-39 vs. < 18 years. Among participants with severe symptoms, females vs. males, and participants 18-39 vs. < 18 years had worse HRQL. At least 4 years since worst reaction was associated with worse HRQL for participants 40+ years vs. < 18 years, and older males vs. males < 18 years. Nearly all differences exceeded the clinical relevance threshold of ≥ 0.5.
CONCLUSIONS
CONCLUSIONS
Associations between allergies to common foods and HRQL are affected by gender and age. Most affected are males 18-39 years. Among females, HRQL is more stable across age groups.
Identifiants
pubmed: 31507642
doi: 10.1186/s13223-019-0370-1
pii: 370
pmc: PMC6727333
doi:
Types de publication
Journal Article
Langues
eng
Pagination
54Investigateurs
Sven-Arne Jansson
(SA)
Eva Östblom
(E)
Marianne Heibert Arnlind
(MH)
Ulf Bengtsson
(U)
Ingrid Kallström-Bengtsson
(I)
Birgitta Marklund
(B)
Georgios Rentzos
(G)
Ann-Charlotte Sundqvist
(AC)
Johanna Åkerström
(J)
Déclaration de conflit d'intérêts
Competing interestsThe authors declare that they have no competing interests.
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