Maternal plasma fetuin-A levels in fetal growth restriction: A case-control study.
Fetuin-A
Pregnancy.
Fetal growth restriction
Journal
International journal of reproductive biomedicine
ISSN: 2476-4108
Titre abrégé: Int J Reprod Biomed
Pays: Iran
ID NLM: 101679102
Informations de publication
Date de publication:
Jul 2019
Jul 2019
Historique:
received:
23
06
2018
revised:
24
12
2018
accepted:
30
04
2019
entrez:
12
9
2019
pubmed:
12
9
2019
medline:
12
9
2019
Statut:
epublish
Résumé
Higher Fetuin-A (FA) concentrations were found to be associated with obesity and there is an interest to the relation between maternal FA and pregnancy outcomes. In this study, our aim was to evaluate the association of maternal plasma levels of FA with fetal growth restriction (FGR). 41 pregnant women with FGR and 40 controls were recruited in this case-control study between July and November 2015. At the diagnosis of FGR, venous blood samples (10 cc) were obtained for FA analysis. Maternal plasma FA levels were significantly higher in fetal growth-restricted pregnant women compared with controls (19.3 The results of this study show higher maternal plasma levels of FA in FGR. Further studies are needed in order to demonstrate the long-term effects of FA in pregnancies complicated with FGR and early prediction of FGR.
Sections du résumé
BACKGROUND
BACKGROUND
Higher Fetuin-A (FA) concentrations were found to be associated with obesity and there is an interest to the relation between maternal FA and pregnancy outcomes.
OBJECTIVE
OBJECTIVE
In this study, our aim was to evaluate the association of maternal plasma levels of FA with fetal growth restriction (FGR).
MATERIALS AND METHODS
METHODS
41 pregnant women with FGR and 40 controls were recruited in this case-control study between July and November 2015. At the diagnosis of FGR, venous blood samples (10 cc) were obtained for FA analysis.
RESULTS
RESULTS
Maternal plasma FA levels were significantly higher in fetal growth-restricted pregnant women compared with controls (19.3
CONCLUSION
CONCLUSIONS
The results of this study show higher maternal plasma levels of FA in FGR. Further studies are needed in order to demonstrate the long-term effects of FA in pregnancies complicated with FGR and early prediction of FGR.
Identifiants
pubmed: 31508574
doi: 10.18502/ijrm.v17i7.4860
pmc: PMC6718885
doi:
Types de publication
Journal Article
Langues
eng
Pagination
487-492Déclaration de conflit d'intérêts
The authors report no conflicts of interest.
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