Identification of antigenic epitopes in the haemagglutinin protein of H7 avian influenza virus.
Amino Acid Sequence
Animals
Antibodies, Monoclonal
/ biosynthesis
Antigens, Surface
/ immunology
Antigens, Viral
/ isolation & purification
Birds
Chick Embryo
Dogs
Epitopes
/ chemistry
Female
Fluorescent Antibody Technique
HEK293 Cells
Hemagglutinins, Viral
/ chemistry
Humans
Influenza A virus
/ immunology
Influenza in Birds
/ immunology
Madin Darby Canine Kidney Cells
Mice
Mice, Inbred BALB C
Sequence Alignment
Tumor Cells, Cultured
Avian influenza virus
H7
epitope
haemagglutinin
identification
monoclonal antibody
Journal
Avian pathology : journal of the W.V.P.A
ISSN: 1465-3338
Titre abrégé: Avian Pathol
Pays: England
ID NLM: 8210638
Informations de publication
Date de publication:
Feb 2020
Feb 2020
Historique:
pubmed:
12
9
2019
medline:
20
5
2020
entrez:
12
9
2019
Statut:
ppublish
Résumé
The H7 subtype avian influenza virus (AIV) has been reported to infect not only poultry but also humans. The haemagglutinin (HA) protein is the major surface antigen of AIV and plays an important role in viral infection. In this study, five monoclonal antibodies (mAbs, 2F8, 3F6, 5C11, 5E2 and 5C12) against the HA protein of H7 virus were produced and characterized. Epitope mapping indicated that
Identifiants
pubmed: 31508993
doi: 10.1080/03079457.2019.1666971
doi:
Substances chimiques
Antibodies, Monoclonal
0
Antigens, Surface
0
Antigens, Viral
0
Epitopes
0
Hemagglutinins, Viral
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM